Fred H. Gage

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Fred Harrison Gage III , called Rusty Gage, (born August 10, 1950 ) is an American neurobiologist at the Salk Institute for Biological Studies in La Jolla , California .

Life

After studying medicine at the University of Florida at Gainesville ( Bachelor's degree ), Gage earned a PhD in neuroscience from Johns Hopkins University . His dissertation topic was A multivariate analysis of social dominance in rats . In 1976 he received his first professorship at Texas Christian University in Fort Worth , Texas , and in 1981 for histology at Lund University in Sweden . In 1985, Gage moved to the Department of Neuroscience at the University of California, San Diego, in La Jolla , California, before becoming a professor of genetics at the Salk Institute for Biological Studies , also in La Jolla.

Act

Gage discovered pluripotent stem cells in the brain and spinal cord of young and adult mammals and thus the structural and functional plasticity of the brain of adult mammals. Gage was able to show that neurons develop in humans throughout life (adult neurogenesis ), that the birth and survival of neurons depend on behavior and that neurotrophins can induce functional recovery processes in damaged or old brains.

Overcoming the old dogma that no new brain cells can develop in adults opens up new therapeutic hopes for people who have suffered a brain trauma or suffer from a neurodegenerative disease .

Gage is one of the most cited scientists in the field of neuroscience. Thomson Reuters has counted him among the favorites for a Nobel Prize ( Thomson Reuters Citation Laureates ) since 2007 .

Awards (selection)

Web links

Individual evidence

  1. Fred H. Gage at Thomson Reuters (thomsonreuters.com); Retrieved November 27, 2012
  2. ^ Neurosciences. (No longer available online.) In: fondation-ipsen.org. Archived from the original on July 21, 2017 ; accessed on February 6, 2016 .
  3. Max Planck Research Prize for Biosciences and Medicine ( Memento from April 3, 2008 in the Internet Archive ) at the Max Planck Society (mpg.de)
  4. ^ Zülch Prize at the Max Planck Society (mpg.de); Retrieved February 18, 2012
  5. Book of Members 1780 – present, Chapter G. (PDF; 931 kB) In: American Academy of Arts and Sciences (amacad.org). Retrieved August 12, 2017 .
  6. The 2008 Keio Medical Science Prize Awardees at Keiō University (keio.ac.jp); Retrieved February 18, 2012
  7. ^ Members: Fred Gage. EMBO, accessed August 15, 2018 .
  8. ^ Member History: Fred H. Gage. American Philosophical Society, accessed August 15, 2018 (with a short biography).