Georg Friedrich Henning
Georg Friedrich Henning (born October 15, 1863 in Wietstock , Cammin district , Pomerania ; † February 21, 1945 in Berlin ) was a German chemist, pharmacist and entrepreneur.
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Georg Friedrich Henning was born as the son of the manor owner August Henning and his wife Ottilie born. Dumstrey was born. He received his education initially in his father's house, later in the cathedral school in Cammin and in the Friedrich-Wilhelm-Realgymnasium Stettin .
As his parents' estate was heavily in debt, Henning had to earn his own living early on, did an apprenticeship as a pharmacist, attended evening school where he could catch up on his Abitur and studied pharmacy and chemistry at the TH Darmstadt and the University of Berlin. Licensed as a pharmacist in 1888, he received his doctorate degree one and a half years later at the University of Erlangen with a contribution to the knowledge of China alkaloids. phil. PhD. After a brief activity at the Institute for the Investigation of Explosives in Spandau, which later became the Military Research Office, he set up his own research laboratory in Berlin in 1892. There Henning u. a. the local anesthetic “Chloraethyl Dr. Henning ”with the active ingredient chloroethane and an artificial shellac .
On July 15, 1898 Georg Friedrich Henning received the DRP patent no. 104280 for a process for the production of a nitro body from hexamethylenetetramine for technical use as an explosive and as a starting material for medical preparations. Henning's invention achieved international importance as an explosive under the name Hexogen (RDX / T4). Even today, hexogen is made from hexamethylenetetramine and is one of the world's most important, highly explosive military explosives. After several smaller companies, which also included dry cleaning, Henning founded the “Chemical and pharmaceutical fabrication Dr. Georg Henning Berlin ”, which he ran as a GmbH until shortly before his death (from 1933 to 1942 with a co-partner) and which he developed into a leading production facility for organotherapy drugs. As early as 1926, Henning brought a DL-thyroxine preparation for the treatment of thyroid disorders under the name "Thyroxin Henning" on the market. The therapy with synthetic thyroid hormones was only able to gain acceptance much later, when the necessary methods for diagnosing thyroid diseases were available. "L-Thyroxin Henning" (Laevothyroxin Sodium), launched in 1967 by the Henning Berlin company, has been one of the most widely prescribed drugs in Germany for many years. Another area of work in which Henning was able to take a leading position as early as the 1930s was the development of processes for the production of nucleosides and nucleotides (ATP, AMP, adenosine, etc.) and their use in the therapy of cardiovascular diseases.
From 1929 to 1939 and again from 1941 to the invasion of the Soviet Army in 1944, Georg Friedrich Henning maintained what is probably the first pharmaceutical joint venture aimed at Eastern Europe with a research-intensive, university-related, originally Polish-Jewish company in Lemberg, which was called "Henning-Laokoon" .
After the Second World War, the descendants of the company owners rebuilt the company founded by Georg Friedrich Henning under the name "Henning Berlin GmbH", with research focus on the thyroid diagnosis and therapy closely linked with the name Henning. Henning Berlin has been part of the Sanofi Group since 1996 .
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- literature
- Xian Wu: Georg Henning - a search for clues , Nachrichten aus der Chemie 66, 2018, pp. 137–145.
- Wolfram Fischer : Henning Berlin, The history of a pharmaceutical company 1913–1991. Duncker & Humblot, Berlin 1992.
- Ullmann's Encyclopedia of Industrial Chemistry. (Point 5.2.3).
- Entry GF Henning. In: German Biographical Encyclopedia. Volume 11, I. Saur, Munich 2000, p. 84.
- Entry GF Henning. In: Biographical encyclopedia of German-speaking entrepreneurs. Römpp, 2004. (Hexogen)
- Enzyclopaedia Britannica. (RDX, hexogen)
Individual evidence
- Web links
| personal data | |
|---|---|
| SURNAME | Henning, Georg Friedrich |
| BRIEF DESCRIPTION | German pharmacist and entrepreneur |
| DATE OF BIRTH | October 15, 1863 |
| PLACE OF BIRTH | Wietstock , Pomerania |
| DATE OF DEATH | February 21, 1945 |
| Place of death | Berlin |