Matthew Henry Gault

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Matthew Henry Gault ( 1925 - May 23, 2003 in St. John's , Newfoundland and Labrador ) was a Canadian physician ( nephrology ) and professor at Memorial University of Newfoundland . He and Donald William Cockcroft developed a popular formula for assessing kidney filter function.

Life

Henry Gault first studied psychology with a bachelor's degree and then medicine at McGill University , where he also received his doctorate in medicine ( MD 1953). He also received training in experimental medicine and completed his specialist training in nephrology and training in medicinal chemistry at the Royal Victoria Hospital. From 1960 to 1974 he was director of the clinical chemistry department and from 1963 to 1974 director of nephrology at Queen Mary Veterans' Hospital (QMVH) in Montreal . He was also director of nephrology at the Royal Victoria Hospital in Montreal from 1970 to 1974. He was Professor of Nephrology at Memorial University (Health Science Center) since 1974 , Head of the Department of Nephrology at the General Hospital (1974 to 1988) and from 1974 to 1993 Director of the Nephrology Laboratory at the General Hospital in St. John's. In 1993 he became professor emeritus .

He was married and had two sons.

plant

Together with Donald William Cockcroft - then resident at the Queen Mary Veterans' Hospital in Montreal - Gault developed the Cockcroft-Gault formula in 1973 for estimating the creatinine clearance from the serum . In nephrology, this creatinine clearance is regarded as identical to the glomerular filtration rate (GFR) and also to primary urine formation. The joint publication with Cockcroft is a Science Citation Classic that has been cited over ten thousand times since 1976.

The Cockcroft-Gault approximation formula dispenses with the 24-hour urine collection , because the creatinine concentration in the urine is no longer required to estimate the GFR. In addition to the creatinine level in the blood, this estimation formula only asks about age, weight and gender. Today this formula is largely being replaced by the MDRD formula and the CKD-EPI formula , because the laboratory does not even need the body weight , but also the skin color (" race ") of the patient to determine it.

His work was an essential diagnostic basis for the decision to go for kidney dialysis and kidney transplants .

Honors

Gault received the Medical Award from the Kidney Foundation of Canada in 1989, became an officer of the Order of Canada in 1991 , received the Commemorative Medal for the 125th anniversary of the Confederation of Canada in 1992 and the Laureate Award from the American College of Physicians in 1993 . In 1988 he became President of the Canadian Association of Nephrology. He received the Atlantic Provinces Laureate Award. In 1966 he received a Masters in Medical Research.

Web links

Individual evidence

  1. Willibald Pschyrembel: Clinical Dictionary , 267th edition, de Gruyter , Berlin / Boston 2017, ISBN 978-3-11-049497-6 , p. 347.
  2. Gerd Herold : Internal Medicine , self-published , Cologne 2019, ISBN 978-3-9814660-8-9 , p. 604.
  3. ^ Donald William Cockcroft, Matthew Henry Gault: Prediction of creatinine clearance from serum creatinine , in: Nephron, Volume 16, Issue 1, 1976, pp. 31-41.
  4. ^ The Merck Manual , 20th edition, Merck, Sharp & Dohme , Kenilworth (New Jersey) 2018, ISBN 978-0-911910-42-1 , p. 2055.
  5. Ulrich Kuhlmann et al. (Ed.): Nephrology , 6th edition, Georg Thieme Verlag , Stuttgart / New York 2015, ISBN 978-3-13-700206-2 , p. 32.