Karl Otto Greulich

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Karl Otto Greulich (born December 19, 1946 in Heidelberg ) is a German laser physicist , biophysicist , gerontologist and former professor at the University of Jena .

life and work

After completing his military service in September 1967, Greulich began studying physics , chemistry and mathematics at the Ruprecht-Karls-Universität Heidelberg , which he graduated in 1973. He then worked as a research assistant at the University of Heidelberg and received his doctorate in 1976 with a thesis on enzyme kinetics under high pressure: Development of a model with application to the enzymatic synthesis of dextras . In the following years he worked at the Physico-Chemical Institute in Heidelberg and completed a one-year research stay in Israel. In November 1989 Greulich completed his habilitation on temporally and spatially high-resolution methods for spectroscopy and micro-processing of organic materials . From April 1990 Greulich held a professorship, but moved to Jena in 1992 and was given a chair in biophysics there in 1993. His working group dealt with applications of lasers in cell and molecular biology . The techniques developed there should make it possible, for example , to experimentally simulate the influence of changes in blood pressure on the endothelial cells or damage caused by a heart attack . Another area was the study of the mechanism of DNA repair , also using laser technology, and its effects on aging . As part of cancer research , the group investigated genetic influences on cancer and supported the Warburg hypothesis with its investigations , restricting it to certain types of tissue . The working group was dissolved in March 2012.

Another field of activity Greulich is the development of new fundamental physical theories , which he began already during his time as head of the working group. According to Greulich, these theories should one day be able to replace large parts of modern physics. They are limited to elementary mathematics . He supports his theses with certain arithmetic relationships between important natural constants . The gravity it leads to the Coulomb back. Since both forces can act between two bodies and decrease with the square of the distance and are proportional to certain properties of the body - mass or charge - the magnitude of the gravitational force can be written as the amount of the Coulomb force by multiplying suitable distance-independent factors . However, it does not describe the direction of the force, the Coulomb force has the property that bodies repel (two positively or two negatively charged bodies) or attract (oppositely charged bodies), which fundamentally differentiates them from gravity, which always has an attractive effect. According to Greulich's own statements, this problem has not yet been solved (as of 2011). Greulich also seeks to replace the established theories of quantum physics . According to his statements, he has found a way to describe experimentally proven violations of Bell's inequality using a classical theory. These violations are widely seen as a strong argument for the need for quantum physics. He tries to explain the interference of individual photons in a non-quantum-physical way, through which the wave-particle dualism is supposed to be superfluous.

Greulich is a member of the advisory board of the conference series “Lasers in the Life Sciences” and “The Nature of Light: What are Photons?”.

He is married and has two sons.

literature

  • Karl Otto Greulich: Micromanipulation by Light: Microbeams and Optical Tweezers (Methods in Bioengineering) . Birkhäuser Boston, February 1, 1999, ISBN 978-3-7643-3873-2
  • Michael W. Berns, Karl Otto Greulich: Laser Manipulation of Cells and Tissues (Methods in Cell Biology) . Academic Pr Inc, June 4, 2007, ISBN 978-0-12-370648-5

Individual evidence

  1. ^ Biography of Karl Otto Greulich
  2. Laser microtools on the group's website
  3. ^ Paulius Grigaravicius, Alexander Rapp, Melanie Struwe, Brigitte Altenberg, Laser microtools and early events of DNA repair
  4. Petra Spamer: Healthy Aging. In: welt.de. May 7, 2008, accessed April 21, 2019 .
  5. Karl Otto Greulich, Brigitte Altenberg, Multi-tissue analysis of gene expression patterns in 24 tissues and changes in their cancers
  6. ^ Website of the Fritz Lipmann Institute
  7. a b What gives elementary particles mass? Article in Focus from January 16, 2012
  8. High accuracy calculation of the masses of all fundamental elementary particles (PDF; 145 kB) , paper from 2010
  9. A surprisingly close relationship between gravitation and electrostatic interactio ( MS PowerPoint ; 251 kB) , lecture from 2011
  10. Another loophole for the Bell inequalities (PDF; 6.8 MB) , paper from 2009
  11. A nonquantum mechanical explanation of the single photon double slit experiment (PDF; 8.3 MB) , paper from 2009

Web links