Lutz Friedjan Tietze

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Lutz Friedjan Tietze (born March 14, 1942 in Berlin ) is a German chemist . Since 1978 he has been Professor of Organic Chemistry at the Faculty of Chemistry at the Georg-August University in Göttingen .

Life

Lutz Friedjan Tietze is the son of the district court director Friederich Tietze and Hete-Irene Tietze, nee. Kruse. He completed his studies at the Universities of Kiel and Freiburg with a diploma in 1966. This was followed by a doctorate under the direction of Burchard Franck on the subject of “Investigations into the targeted oxidation of laudanosoline derivatives”, also at the University of Kiel .

After a research stay with George Büchi at the Massachusetts Institute of Technology in Cambridge (USA) and with Alan R. Battersby at the University of Cambridge (England), he completed his habilitation in 1975 at the University of Münster with the topic “Secologanin, key compound in the biosynthesis of indole -, ipecacuanha and cinchona alkaloids. Studies on Biogenesis and Synthesis ". In the same year he was appointed private lecturer.

In 1977 he was offered a professorship at the University of Dortmund , which he left in 1978 to accept a professorship at the Faculty of Chemistry at the Georg-August University in Göttingen . He turned down a call to Münster in 1992. Tietze has published 452 publications and 4 books so far (March 2010) and received 32 patents .

Lutz Friedjan Tietze has been with Karin, geb. Krautschneider, married. The two have four children.

Research priorities

  • Development of selective and efficient synthetic methods ( domino reactions , transition metal-catalyzed transformations, enantioselective allylation of ketones). He was instrumental in the development of the term and the categorization of domino reactions.
  • Total synthesis of natural substances ( terpenes , steroids , alkaloids , macrolactones , antibiotics , anti-cancer drugs). Particularly noteworthy here are the total syntheses of vitamin E , hirsutin and indomycinones.
  • High pressure syntheses
  • Combinatorial chemistry in solutions and on the solid phase.
  • Development of new cytotoxic compounds and vaccines for selective cancer therapy using monoclonal antibodies and ganglioside analogs.

Visiting professorships

  • 1978 Hamburg
  • 1982 Madison, Wisconsin / USA
  • 1995 Strasbourg, France
  • 1999 Sydney, Australia
  • 2001 Bologna, Italy
  • 2003 Paris, France

Awards (selection)

Works

  • What's cooking in chemistry? Wiley-VCH-Verlag, Weinheim 2009
  • Domino reactions in organic synthesis. Wiley-VCH-Verlag, Weinheim 2006
  • Reactions and syntheses in the organic chemistry laboratory. Wiley-VCH, Weinheim 2006
  • Preparativnaja organičeskaja chimija. Mir, Moskva 1999, Učebnoe izd
  • Seimitsu-yūki-kōsei. Nankōdō, Tōkyō 1995, Kaitei, 2 han
  • with Theophil Eicher: Basic organic chemical internship taking into account the Ordinance on Hazardous Substances. Thieme, Stuttgart 1993; 2. rework. Edition 1995; [2001]
  • Reactions and syntheses in the organic-chemical internship. Thieme, Stuttgart 1981; 2., rework. Edition 1991; [2001]
  • Investigation of the targeted oxidation of laudanosoline derivatives. Kiel 1968

literature

Web links