Mestanolone

Structural formula
General
Non-proprietary name	Mestanolone
other names	17 α -methyl-17 β -hydroxy-5 α -androstan-3-one; (5 S , 8 R , 9 S , 10 S , 13 S , 14 S , 17 S ) -17-hydroxy-10,13,17-trimethyl-2,4,5,6,7,8,9,11 , 12,14,15,16-dodecahydro-1 H -cyclopenta [ a ] phenanthren-3-one ( IUPAC );
Molecular formula	C 20 H 32 O 2
External identifiers / databases
EC number	208-302-6
ECHA InfoCard	100.007.549
PubChem	10633
ChemSpider	10187
Wikidata	Q1924446
Drug information
Drug class	Anabolic steroids
properties
Molar mass	304.47 g · mol -1
safety instructions
GHS labeling of hazardous substances Caution
H and P phrases	H: 351
	P: ?
Toxicological data	> 3000 mg kg −1 ( LD 50 , rat , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Mestanolone (also known under the name STS 646 or M2) is a methyl - derivative of dihydrotestosterone , which as anabolic steroid absence of clinical admission especially in state-organized doping system in the GDR competitive sport was in use.

Mestanolone has an androgenic effect of 97 points and an anabolic effect of 53 points (determined with the Hershberger test ). Since the intake is associated with a comparatively small increase in the athlete's body mass, mestanolone was preferably used in sports in which a relatively low body weight was important, such as jumping disciplines, gymnastics, figure skating, long-distance running and the lower weight classes in boxing and wrestling and judo. Mestanolone was also often taken in combination with Oral-Turinabol . The production in the GDR took place at VEB Jenapharm .

Individual evidence

↑ Template: CL Inventory / not harmonized There is not yet a harmonized classification for this substance . A labeling of mestanolone in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), which was retrieved on July 8, 2020, is reproduced from a self-classification by the distributor .
↑ Entry on mestanolone in the ChemIDplus database of the United States National Library of Medicine (NLM), accessed on July 8, 2020.
↑ Brigitte Berendonk: Doping documents - From research to fraud. Springer-Verlag, Berlin 1991, ISBN 3-540-53742-2 , p. 80, table 3.
↑ Brigitte Berendonk: Doping documents - From research to fraud. Springer-Verlag, Berlin 1991, ISBN 3-540-53742-2 , p. 111.

[1] Template: CL Inventory / not harmonized There is not yet a harmonized classification for this substance . A labeling of mestanolone in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), which was retrieved on July 8, 2020, is reproduced from a self-classification by the distributor .

[ChemIDplus-2] Entry on mestanolone in the ChemIDplus database of the United States National Library of Medicine (NLM), accessed on July 8, 2020.

[BB-DD-80-3] Brigitte Berendonk: Doping documents - From research to fraud. Springer-Verlag, Berlin 1991, ISBN 3-540-53742-2 , p. 80, table 3.

[BB-DD-111-4] Brigitte Berendonk: Doping documents - From research to fraud. Springer-Verlag, Berlin 1991, ISBN 3-540-53742-2 , p. 111.