Methyl azoxymethyl acetate

Structural formula
General
Surname	Methyl azoxymethyl acetate
other names	(Methyl-ONN-azoxy) methyl acetate; MAM acetate;
Molecular formula	C 4 H 8 N 2 O 3
Brief description	colorless liquid
External identifiers / databases
EC number	209-765-7
ECHA InfoCard	100,008,879
PubChem	5363199
Wikidata	Q4073291
properties
Molar mass	132.12 g mol −1
Physical state	liquid
density	1.172 g cm −3
boiling point	191 ° C
solubility	sparingly soluble in water and ether; miscible with chloroform;
safety instructions
GHS hazard labeling from Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary danger
H and P phrases	H: 350-360D
	P: ?
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Methyl azoxymethyl acetate is a chemical compound from the group of carboxylic acid esters and the aglycon of cycasin .

properties

Methyl azoxymethyl acetate is a colorless liquid that easily hydrolyzes in water, especially under alkaline conditions.

use

Methyl azoxymethyl acetate is used in medical research. It leads to brain developmental disorders in rats similar to those that occur in schizophrenia.

Individual evidence

↑ ^a ^b ^c ^d ^e ^f Entry on (methyl-ONN-azoxy) methyl acetate in the GESTIS substance database of the IFA , accessed on December 30, 2019(JavaScript required) .
^ ^A ^b ^c ^d Bela Toth: Hydrazines and Cancer: A Guidebook on the Carciognic Activities of Hydrazines, Related Chemicals, and Hydrazine Containing Natural Products . CRC Press, 2003, ISBN 978-0-203-30509-6 ( books.google.com ).
↑ Entry on (methyl-ONN-azoxy) methyl acetate in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on December 30, 2019. Manufacturers or distributors can expand the harmonized classification and labeling .
↑ Nicholas P. Cheremisinoff: Dangerous Properties of Industrial and Consumer Chemicals . CRC Press, 1994, ISBN 978-0-8247-9183-4 ( books.google.com ).
↑ Mikhail Pletnikov, John Waddington: Modeling the Psychopathological Dimensions of Schizophrenia: From Molecules to Behavior . Academic Press, 2015, ISBN 978-0-12-801184-3 ( books.google.com ).
↑ Ana L Jongen-Rêlo, Andreas Leng, Marcel Lüber, Helen H. J Pothuizen, Liz Weber, Joram Feldon: The prenatal methylazoxymethanol acetate treatment: a neurodevelopmental animal model for schizophrenia? In: Behavioral Brain Research . tape 149 , no. 2 , March 2, 2004, p. 159-181 , doi : 10.1016 / S0166-4328 (03) 00228-6 ( sciencedirect.com ).

[GESTIS-1] ↑ ^a ^b ^c ^d ^e ^f Entry on (methyl-ONN-azoxy) methyl acetate in the GESTIS substance database of the IFA , accessed on December 30, 2019(JavaScript required) .

[Bela_Toth-2] A ^b ^c ^d Bela Toth: Hydrazines and Cancer: A Guidebook on the Carciognic Activities of Hydrazines, Related Chemicals, and Hydrazine Containing Natural Products . CRC Press, 2003, ISBN 978-0-203-30509-6 ( books.google.com ).

[CLP_100.008.879-3] Entry on (methyl-ONN-azoxy) methyl acetate in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on December 30, 2019. Manufacturers or distributors can expand the harmonized classification and labeling .

[4] Nicholas P. Cheremisinoff: Dangerous Properties of Industrial and Consumer Chemicals . CRC Press, 1994, ISBN 978-0-8247-9183-4 ( books.google.com ).

[5] Mikhail Pletnikov, John Waddington: Modeling the Psychopathological Dimensions of Schizophrenia: From Molecules to Behavior . Academic Press, 2015, ISBN 978-0-12-801184-3 ( books.google.com ).

[6] Ana L Jongen-Rêlo, Andreas Leng, Marcel Lüber, Helen H. J Pothuizen, Liz Weber, Joram Feldon: The prenatal methylazoxymethanol acetate treatment: a neurodevelopmental animal model for schizophrenia? In: Behavioral Brain Research . tape 149 , no. 2 , March 2, 2004, p. 159-181 , doi : 10.1016 / S0166-4328 (03) 00228-6 ( sciencedirect.com ).