Mimetic
Mimetics ( Latinization from ancient Greek μιμητικός mimētikós , German 'belonging to imitation, skillful' ) are chemical compounds that bind to the same receptor as the actual active ingredient . Direct mimetics trigger a cellular signal and are called agonists . If, on the other hand, the receptor is merely blocked, one speaks of antagonists .
Examples
The following act on the parasympathetic nervous system :
- direct parasympathomimetics ( acetylcholine , carbachol , pilocarpine )
- indirect parasympathomimetics ( neostigmine , physostigmine )
- Parasympatholytics ( atropine , ipratropium , scopolamine )
Act on the sympathetic nervous system :
- direct sympathomimetics ( noradrenaline , adrenaline , xylometazoline , salbutamol )
- indirect sympathomimetics ( amphetamine , cocaine , reboxetine )
- Sympatholytics ( prazosin , propranolol )
Selected examples
- β2-agonists are in bronchial asthma used
- Lysergic acid diethylamide is a psychotomimetic
See also
literature
- Claudia Dellas: Last Minute Pharmacology. Urban & Fischer, 2015. ISBN 9783437298004 .
- Eduard Kurt Liebler: Peptide protein mimetics for sequence-specific kinking of DNA. Cuvillier Verlag, Göttingen 2005. ISBN 3865375219 .
- Heinz Lüllmann, Klaus Mohr, Lutz Hein: Pharmacology and toxicology: Understanding the effects of drugs - using drugs in a targeted manner. A textbook for students of medicine, pharmacy and life sciences, a source of information for doctors, pharmacists and health policymakers. Thieme, Stuttgart 2010. ISBN 978-3-13-368517-7 .
Individual evidence
- ^ Wilhelm Pape , Max Sengebusch (arrangement): Concise dictionary of the Greek language . 3rd edition, 6th impression. Vieweg & Sohn, Braunschweig 1914 ( zeno.org [accessed December 5, 2019]).
- ↑ a b c Lüllmann et al .: Pharmacology and toxicology: Understanding drug effects - using drugs in a targeted manner. P. 82ff.
