Monobenzone

Structural formula
General
Surname	Monobenzone
other names	4-benzyloxyphenol; p-benzyloxyphenol; Hydroquinone monobenzyl ether;
Molecular formula	C 13 H 12 O 2
Brief description	light brown odorless solid
External identifiers / databases
EC number	203-083-3
ECHA InfoCard	100.002.804
PubChem	7638
ChemSpider	7356
DrugBank	DB00600
Wikidata	Q2768526
Drug information
ATC code	D11 AX13
properties
Molar mass	200.24 g mol −1
Physical state	firmly
density	1.26 g cm −3
Melting point	117.9-121.5 ° C
solubility	practically insoluble in water; soluble in ethanol, ether, benzene and acetone;
safety instructions
	Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS hazard labeling from Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary Caution
H and P phrases	H: 317-319
	P: 280-302 + 352-305 + 351 + 338
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Monobenzone is a chemical compound from the group of substituted phenols . It is the monobenzyl ether of hydroquinone .

Extraction and presentation

Monobenzone can be obtained by several synthetic methods. One is the reaction of hydroquinone and benzyl bromide in alcoholic potassium hydroxide .

properties

Monobenzone is a flammable brownish white odorless solid that is practically insoluble in water.

use

Monobenzone is used as a drug ingredient, stabilizer, antioxidant and polymerization inhibitor. It is used in dermatology as a bleaching agent for pigmented areas with pronounced vitiligo .

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ Entry on monobenzone in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .
↑ ^a ^b Entry on monobenzone in the Hazardous Substances Data Bank , accessed September 2, 2014.
↑ Entry on Monobenzone in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .

[GESTIS-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ Entry on monobenzone in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .

[HSDB-2] Entry on monobenzone in the Hazardous Substances Data Bank , accessed September 2, 2014.

[CLP_100.002.804-3] Entry on Monobenzone in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .