The genus Omikronpapillomavirus (named after the Greek letter omikron ) contains only one species of the family Papillomaviridae , which was isolated from genital warts and papillomas on the tongue in Burmeister's porpoises ( Phocoena spinipinnis ), the Phocoena spinipinnis papillomavirus (PsPV). PsPV is the only papilloma virus found to date that causes genital warts in non- primates . There is evidence of two different species or subtypes of this virus, tentatively referred to as PsPV-1 and -2. Three new virus isolates from dolphins ( bottlenose dolphin , Tursiops truncatus ) suggest a recombination of different papillomavirus species across different genera of papillomaviruses. The isolates not yet classified were named Tursiops truncatus papillomavirus (TtPV-1, -2 and -3).
Typical for the genus omicron papillomavirus is the lack of a gene for the E7 protein , which interacts with the tumor suppressor gene RB105 in the cell nucleus and activates various cellular promoters . Three additional reading frames within the reading frame for the capsid protein L1 are also characteristic . The function of these gene products and their actual existence and importance during virus replication are not known.
Systematics
With the reorganization of the Papillomaviridae , the ICTV introduced new species names. As of November 2018:
Species omicron papillomavirus 1 syn. obsolete Phocoena spinipinnis papillomavirus (PsPV)
swell
Ethel-Michele de Villiers, et al. : Genus Omicron Papillomavirus . In: CM Fauquet, MA Mayo et al. : Eighth Report of the International Committee on Taxonomy of Viruses . London, San Diego 2005, pp. 243ff ISBN 0-12-249951-4
↑ Marie-Francoise Van Bressem et al. : Genital warts in Burmeister's porpoises: characterization of Phocoena spinipinnis papillomavirus type 1 (PsPV-1) and evidence for a second, distantly related PsPV . J. Gen. Virol. (2007) 88 (Pt 7): pp. 1928-1933 PMID 17554024
