Perfluorohexanesulfonic acid
| Structural formula | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
||||||||||||||||
| General | ||||||||||||||||
| Surname | Perfluorohexanesulfonic acid | |||||||||||||||
| other names |
|
|||||||||||||||
| Molecular formula | C 6 HF 13 O 3 S. | |||||||||||||||
| External identifiers / databases | ||||||||||||||||
|
||||||||||||||||
| properties | ||||||||||||||||
| Molar mass | 400.11 g mol −1 | |||||||||||||||
| Physical state |
firmly |
|||||||||||||||
| safety instructions | ||||||||||||||||
|
||||||||||||||||
| Authorization procedure under REACH |
of particular concern : very persistent and very bioaccumulative ( vPvB ) |
|||||||||||||||
| As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . | ||||||||||||||||
Perfluorohexanesulfonic acid (short name PFHxS ) is a chemical compound from the group of long-chain perfluorosulfonic acids . Their anion , the perfluorohexanesulfonate, is important.
Perfluorohexanesulfonate is produced by electrochemical fluorination . In contrast to the related perfluorohexanoic acid , but analogous to the longer-chain perfluorooctanesulfonic acid , perfluorohexanesulfonic acid is bioaccumulative . Up to 2014 only one study on the toxicological effects was known. This shows no negative effects, although the scope of the study does not allow a final assessment. PFHxS has been nominated for inclusion in the Stockholm Convention . In 2017, PFHxS was included in the candidate list according to the REACH regulation and the Federal Environment Agency recommended a drinking water conductivity of 0.1 µg / l. In 2019, it was proposed to include it in the substance in Annex XVII of the REACH regulation; The European Chemicals Agency will form an opinion on this by mid-2020. Impairment of the liver and the immune response, shown as a decreased antibody response to vaccines, are now known as possible effects on humans.
The connection was z. B. contained in the impregnation agent Scotchgard .
Individual evidence
- ↑ a b Perfluorohexanesulfonic acid. Safety Data Sheet 616432T In: synquestlabs.com , accessed October 18, 2017 (PDF; 184 kB)
- ↑ Entry in the SVHC list of the European Chemicals Agency , accessed on July 10, 2017.
- ↑ DuPont Capstone® Repellents and Surfactants ( Memento of May 18, 2016 in the Internet Archive ), p. 22.
- ^ Minnesota Department of Health: Summary Sheet: PFHxS , accessed September 8, 2016.
- ^ Norway proposes adding second PFC to UN POPs Convention . In: chemicalwatch.com . (Registration required)
- ↑ Martin Heidenreich: The REACH candidate list has 174 substances of very high concern. August 11, 2017. Retrieved November 28, 2019 .
- ↑ REACH: Perfluorohexanesulfonic acid (PFHxS) added to the candidate list in July 2017. Retrieved November 28, 2019 (German).
- ↑ Update of the preliminary assessment of perfluorinated and polyfluorinated chemicals (PFC) in drinking water: Recommendation of the Federal Environment Agency after hearing the Drinking Water Commission . In: Federal Health Gazette - Health Research - Health Protection . tape 60 , no. 3 , March 2017, ISSN 1436-9990 , p. 350–352 , doi : 10.1007 / s00103-016-2508-3 ( springer.com [accessed November 28, 2019]).
- ↑ EU: REACH Annex XVII restriction on PFHxS was proposed. Accessed November 28, 2019 .
- ↑ S. Beesoon, S. Genuis, J. Benskin, J. Martin: Abnormally High Serum Levels of Perfluorohexane Sulfonate (PFHxS) in A Canadian Family - A Case Study , Organohalogen Compounds, 2010.