Peter J. Moloney
Peter Joseph Moloney (born June 29, 1891 in Penetanguishene , Ontario , † August 12, 1989 in Toronto , Ontario) was a Canadian chemist who has made a particular contribution to the development of vaccines and insulin preparations .
Moloney introduced toxoid vaccines against diphtheria and tetanus , demonstrated antibodies to insulin in humans and animals, and developed sulfated insulin preparations for the treatment of diabetics with insulin resistance .
Live and act
Moloney was the son of an Irish immigrant. He earned a bachelor's degree in chemistry from the University of Toronto in 1912 and a master's degree in 1915 . During a stay at the University of California at Berkeley in 1915/1916 he met his future wife Angelina Chapman; the couple had five children. Moloney worked in the Department of Agriculture in Ottawa in food chemistry from 1917 to 1919 .
From 1919 he worked as a research assistant for Connaught Laboratories , a vaccine manufacturer that emerged from the University of Toronto and is now part of Sanofi . Moloney initially dealt with the diphtheria toxin , the provision of which he directed from 1924. After earning a Ph.D. From 1921 he was entrusted with the purification of insulin in the work group of Charles Best and Frederick Banting in order to make it clinically usable, which was first achieved in 1922.
Moloney helped to develop a detection test for the diphtheria toxin and established methods for the detection and purification of tetanus toxin and contributed to the elucidation of its antigen structure . From 1931 he headed the chemistry department of the School of Hygiene ( microbiology ) at the university. He was part of the group that successfully developed methods of making penicillin on a large scale during World War II . Moloney and co-workers were also able to produce a polyvalent immune serum against gas fire .
From 1925 until his retirement in 1961, he was deputy director of Connaught Laboratories, but remained a researcher and consultant for the company until he was nine years old. His last publications in the early 1970s dealt with insulin resistance and insulin as an antigen . Moloney owned several patents, including those relating to the manufacture of insulin and the manufacture of heparin . He applied for his last patent when he was 90 years old. In 1977 Connaught Laboratories Ltd. the Moloney Building opens.
Moloney was considered a devout Catholic.
Awards (selection)
- 1936 member of the Royal Society of Canada
- 1946 Order of the British Empire
- 1962 Honorary Member of the Canadian Public Health Association (CPHA)
- 1964 Banting Medal of the American Diabetes Association
- 1967 Gairdner Foundation International Award
- 1971 Honorary Doctorate from the University of Toronto
- 1971 Charles H. Best Medal
Web links
- Peter Joseph Moloney at science.ca
- Profiles in Public Health: Peter J. Moloney at the Canadian Public Health Association (cpha.ca)
- www.drpetermoloney.com - private website with biographical information
Individual evidence
- ^ Fellows of the Royal Society of Canada (rsc-src.ca); accessed on March 28, 2014
- ↑ Peter J. Moloney OBE, PhD, FRSC at the Gairdner Foundation (gairdner.org); accessed on March 28, 2014
| personal data | |
|---|---|
| SURNAME | Moloney, Peter J. |
| ALTERNATIVE NAMES | Moloney, Peter; Moloney, Peter Joseph (full name) |
| BRIEF DESCRIPTION | Canadian chemist |
| DATE OF BIRTH | June 29, 1891 |
| PLACE OF BIRTH | Penetanguishene , Ontario |
| DATE OF DEATH | August 12, 1989 |
| Place of death | Toronto , Ontario |