Peter Wich

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Peter R. Wich is a German chemist and university professor ( macromolecular chemistry , biopolymers , bio-organic chemistry , supramolecular chemistry ).

Career

Wich studied chemistry at Julius-Maximilians-Universität Würzburg with a diploma in 2005 (Substrate selectivity of artificial peptide receptors - Synthesis and screening of a combinatorial library of tetrapeptides) and also studied in 2003 at Heriot-Watt University with Dave R. Adams in Edinburgh (UK). In 2005/06 he was at the University of California, San Diego with Jerry Yang and then again in Würzburg, where he received his doctorate in organic chemistry with Carsten Schmuck in 2009 (Multifunctional oligopeptides as an artificial toolkit for molecular recognition events) . Both the diploma and the dissertation received the faculty award. As a post-doctoral student , he worked with Jean Fréchet at the University of California, Berkeley from 2010 to 2012 . In 2012 he became junior professor for medicinal / pharmaceutical chemistry at Johannes Gutenberg University Mainz . In 2018 he accepted a position as a professor at the University of New South Wales (UNSW) in Australia, where he is currently researching and teaching as a Senior Lecturer at the School of Chemical Engineering.

Research priorities

His research focuses on macromolecular chemistry at the interface between nanotechnology and bio-organic chemistry. In his dissertation, he dealt with construction kits made of multifunctional oligopeptides , with which he investigated the function of enzymes and molecular recognition processes. With the beginning of his independent academic research career, his work focused on the chemical modification of natural biopolymers (sugars and proteins) with the aim of developing new multifunctional and biocompatible nanomaterials for applications in drug delivery and catalysis (e.g. polysaccharide - and protein - based nanoparticle platforms for the transport of therapeutically relevant active substances such as siRNA or cancer drugs; the development of artificial enzymes and catalytically active nanomaterials).

He is active in popularizing chemistry and has been running the Experimental Chemistry Internet platform for chemical demonstration experiments since 2001 .

Honors and memberships

Wich was a scholarship holder of the German National Academic Foundation and Fedor Lynen was a fellow of the Alexander von Humboldt Foundation . In 2016 he became a member of the Academy of Sciences and Literature Mainz .

In 2014 he received the innovation award of the Society of German Chemists (GDCh) and the German Pharmaceutical Society (DPhG) for his research .

In 2017, together with Carsten Schmuck and Tanja Schirmeister, he received the literature prize of the Fonds der Chemischen Industrie for their work on the new edition of the textbook Beyer-Walter Organic Chemistry .

In 2017 he was awarded the Galenus Technology Prize (a biannual prize for innovative work in the field of pharmaceutical technology).

Fonts (selection)

  • with M. Fach, L. Radi: Nanoparticle Assembly of Surface-Modified Proteins , J. Am. Chem. Soc., Volume 138, 2016, pp. 14820-14823.
  • with C. Schmuck and T. Schirmeister (editor): Beyer / Walter Textbook of Organic Chemistry, 25th edition, Hirzel 2016.
  • with B. Breitenbach, I. Schmid: Amphiphilic Polysaccharide Block Copolymers for pH-Responsive Micellar Nanoparticles , Biomacromolecules, Volume 18, No. 9, 2017, pp. 2839-2848.
  • with C. Ornelas-Megiatto, JMJ Fréchet: Polyphosphonium Polymers for siRNA Delivery: An Efficient and Non-Toxic Alternative to Polyammonium Carriers , J. Am. Chem. Soc., Volume 134, 2012, pp. 1902-1905.
  • with F. Foerster, D. Bamberger, J. Schupp, M. Weilbächer, L. Kaps, S. Strobl, L. Radi, M. Diken, D. Strand, A. Tuettenberg, D. Schuppan: Dextran-based Therapeutic Nanoparticles for Hepatic Drug Delivery , Nanomedicine, Volume 11, 2016, pp. 2663-2677.
  • with C. Ornelas-Megiatto, Fréchet a. a .: Aerosolized Antimicrobial Agents Based on Degradable Dextran Nanoparticles Loaded with Silver Carbene Complexes , Mol. Pharmaceutics, Volume 9, 2012, pp. 3012-3022.
  • with JL Cohen, Fréchet u. a .: Acid-Degradable Cationic Dextran Particles for the Delivery of siRNA Therapeutics , Bioconjugate Chem., Volume 22, 2011, pp. 1056-1065.
  • with C. Schmuck: Reversible and Non-Competitive Inhibition of β-Tryptase by Tetravalent Peptide Ligands Identified from a Combinatorial Split-Mix-Library , Angew. Chem. Int. Ed., Vol. 49, 2010, pp. 4113-4116.

Web links

Individual evidence

  1. ↑ WichLab.com where it is shown in more detail research.
  2. ↑ Experimentalchemie.de
  3. ↑ Innovation Prize for Wich, University of Mainz , 2014
  4. ↑ Literature Prize of the Chemical Industry 2017 for textbook on organic chemistry - Verband der Chemischen Industrie eV (VCI). Retrieved February 3, 2018 .
  5. ↑ Galenus Privatstiftung: Technologie-Preis 2017. Retrieved on February 3, 2018 .
personal data
SURNAME Wich, Peter
ALTERNATIVE NAMES Wich, Peter R.
BRIEF DESCRIPTION German chemist
DATE OF BIRTH 20th century