Phil Baran

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Phil S. Baran (born August 10, 1977 in Denville (New Jersey) ) is an American chemist. He deals with organic synthesis ( total synthesis ), especially biologically active and pharmacologically interesting natural products.

life and work

Baran received his bachelor's degree from New York University in 1997 and his PhD from the Scripps Research Institute in La Jolla in 2001 . From 2001 to 2003 he was a post-doctoral student at Harvard University before becoming an assistant professor at the Scripps Research Institute. In 2006 he became Associate Professor and in 2008 Professor. He has been a member of the Skaggs Institute for Chemical Biology since 2009.

He developed new methods of organic synthesis of a wide range of important natural products (from indoles to terpenes ), which are also suitable for mass production. Recently, for example, he synthesized cortistatin A, a steroid alkaloid from marine life that shows promising properties for preventing angiogenesis with medical applications in cancer therapy and ophthalmology, and ouabagenin , a steroid that is used in cardiology.

In 2011, he found a safe way to incorporate fluorine into organic compounds, which is used, among other things, to increase the efficiency of drugs that are less rapidly broken down in the liver. He received a MacArthur Fellowship in 2013.

A number of reagents developed by him are marketed as Baran Reagents by Sigma Aldrich.

Honors and memberships

  • 2000 Hoffmann-La Roche Award for Excellence in Organic Chemistry
  • 2005 Amgen Young Investigator Award and Astra Zeneca Excellence in Chemistry Award
  • 2005–2006 Eli Lilly Young Investigator Award and Glaxo SmithKline Chemistry Scholar Award
  • 2005 DuPont Young Professor Award
  • 2006 Pfizer Award for Creativity in Organic Chemistry
  • 2007 Fresenius Award and Hirata Gold Medal
  • 2007/2008 Novartis Lecturer
  • 2010 American Chemical Society Award in Pure Chemistry ,
  • 2010 Thieme-IUPAC Prize in Synthetic Organic Chemistry
  • 2009 Sackler Prize
  • 2012 Howard Memorial Lecture, University of Sydney
  • In 2013 he became a MacArthur Fellow .
  • 2013 Synthetic Organic Chemistry Award from the Royal Society of Chemistry
  • 2015 member of the American Academy of Arts and Sciences
  • 2017 member of the National Academy of Sciences
  • 2019 Inhoffen Medal

From 2006 to 2008 he was a Sloan Fellow and from 2006 to 2010 he received an NSF Career Award.

Fonts

  • with KC Nicolaou , Dionisios Vourloumis, Nicolas Winssinger: The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century , Angewandte Chemie, International Edition, Volume 39, 2000, pp. 44–122

Web links

supporting documents

  1. ^ Organic chemist Phil Baran , NPR, September 25, 2013, accessed October 8, 2018
personal data
SURNAME Baran, Phil
ALTERNATIVE NAMES Baran, Phil S.
BRIEF DESCRIPTION American chemist
DATE OF BIRTH August 10, 1977
PLACE OF BIRTH Denville, New Jersey