Sheldon M. Wolff

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Sheldon Malcolm "Shelly" Wolff (born August 19, 1930 in Newark , New Jersey , † February 9, 1994 in Boston ) was an American internist and inflammation researcher .

Life

Wolff earned a bachelor's degree from the University of Georgia in 1952 , spent two years abroad at the Ruprecht-Karls-Universität Heidelberg and studied medicine at Vanderbilt University with an MD in 1957. He completed his specialist training in internal medicine at Vanderbilt University and the Bronx Municipal Medical Center . In 1960 he became a research assistant at Vernon Knight at the National Institute of Allergy and Infectious Diseases (NIAID, a facility of the National Institutes of Health , NIH), whose position as head of the clinical research laboratory and as quasi-chief physician he took over in 1968. In 1977 he moved to Tufts University as a professor of internal medicine and as chief physician at the New England Medical Center Hospital in Boston . In addition, he took on tasks in the national specialist organization for internal medicine (American Board of Internal Medicine) .

Wolff dealt with various infectious diseases and the phenomenon of fever , its causes, its effects on the organism and its role in infections and inflammatory and immunological disorders. His attention was particularly the fever of unknown origin ( fever of unexplained origin , FUO) and familial Mediterranean fever (FMF). He was part of the research group that identified tampons as the most important factor in the development of toxic shock syndrome . Together with Anthony Fauci , he developed therapy schemes for the treatment of granulomatosis with polyangiitis , polyarteritis nodosa and other necrotizing vascular diseases. Together with Charles Dinarello , he was able to make important contributions to understanding the role of interleukin-1 in the immune system. At the political level, in the mid-1980s, he succeeded in dramatically increasing government funding for AIDS research .

In 1984 Wolff was elected to the American Academy of Arts and Sciences . In 1992 he received the Alexander Fleming Award from the Infectious Diseases Society of America . He received honorary doctorates from Brandeis University and Tufts University .

Wolff was married and had three children. He died of complications from cancer.

Web links

Individual evidence

  1. Book of Members 1780 – present, Chapter W. (PDF; 852 kB) In: American Academy of Arts and Sciences (amacad.org). Retrieved December 3, 2017 .
  2. IDSA: Alexander Fleming Award Winners. In: idsociety.org. Retrieved December 3, 2017 .