Sodium trimethylsilyl propionate
| Structural formula | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|||||||||||||||||||
| General | |||||||||||||||||||
| Surname | Sodium trimethylsilyl propionate | ||||||||||||||||||
| other names |
|
||||||||||||||||||
| Molecular formula | C 6 H 13 NaO 2 Si | ||||||||||||||||||
| External identifiers / databases | |||||||||||||||||||
|
|||||||||||||||||||
| properties | |||||||||||||||||||
| Molar mass | 168.06 g mol −1 | ||||||||||||||||||
| Physical state |
firmly |
||||||||||||||||||
| safety instructions | |||||||||||||||||||
|
|||||||||||||||||||
| As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . | |||||||||||||||||||
Sodium trimethylsilyl propionate ( TMSP or TSP for short ) is a chemical compound that contains a trimethylsilyl group . TSP is the salt of trimethylsilylpropionic acid, although the literature often does not clearly differentiate between the acid and its salts.
Use in nuclear magnetic resonance
propionate.svg)
The deuterated variant, in which the four central hydrogen atoms are exchanged for deuterium atoms [C 6 H 9 D 4 NaO 2 Si, 3- (trimethylsilyl) propion-2,2,3,3-d4-acid, sodium salt], is used as the reference substance used in NMR spectroscopy . The reason is that the hydrogen atoms in the methyl groups bonded to the silicon have a significantly different resonance frequency than most organic molecules . The signal thus comes to lie at the edge of the NMR spectrum, where there is hardly any fear of overlapping. A chemical shift of 0 ppm is assigned to the signal .
In organic solvents, tetramethylsilane (TMS) is used instead of TSP .
Individual evidence
- ↑ a b Data sheet 3- (Trimethylsilyl) propionic acid sodium salt, 99% from Sigma-Aldrich , accessed on November 5, 2019 ( PDF ).
- ↑ External identifiers or database links to 3- (trimethylsilyl) propion-2,2,3,3-d4-acid sodium salt : CAS number: 24493-21-8, EC number: 246-286-2 , ECHA InfoCard: 100.042.063 , PubChem : 23688921 , ChemSpider : 147108 , Wikidata : Q15496271 .
- ↑ Data sheet 3- (Trimethylsilyl) propionic acid-d 4 sodium salt from Sigma-Aldrich , accessed on April 14, 2011 ( PDF ).