Thomas Bschleipfer

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Thomas Bschleipfer (born January 26, 1972 in Augsburg ) is a German doctor and philosopher. He is a specialist in urology , professor at the Justus Liebig University in Giessen and chief physician at the clinic for urology, andrology and pediatric urology at the Klinikum Weiden / Kliniken Nordoberpfalz AG. Bschleipfer is an expert in the areas of functional urology / bladder dysfunction , urogynecology, interstitial cystitis / bladder pain syndrome (IC / BPS) and benign prostate syndrome (BPS). Scientifically, Bschleipfer dealt in particular with the clinical picture of the overactive bladder (OAB).

In philosophy, Bschleipfer specialized in the field of moral philosophy and dealt intensively with allocation problems . He wrote the first ethics of German crisis and emergency medicine.

Life

After graduating from high school near St. Stephan in Augsburg, Bschleipfer studied human medicine at the University of Ulm (1992–1999) and received his doctorate in 2002 on the subject of "Experimental blunt kidney trauma - biomechanics, trauma behavior and diagnostic imaging". med. "(summa cum laude).

In 1996, Bschleipfer completed his accompanying humanities studies with a focus on philosophy at the Humboldt Study Center of Ulm University on the subject of "virtue ethics - the problem of so-called secondary virtues ". From 1999 to 2007 he was enrolled as an external doctoral student at the BTU Cottbus and received his doctorate at the chair for philosophy of technology with Klaus Kornwachs in 2007 as “Dr. phil. ”(magna cum laude). The topic of the thesis was "Ethics of a Crisis Medicine - Critical Analysis of Area-Specific Dilemmas: Resource Allocation, Instrumentalization and Double Loyalty".

After working in the surgery, urology and anesthesia departments at the Bundeswehr Hospital in Ulm (1999–2001), Bschleipfer was a medical officer and aviator of the Airborne Warning and Control System (AWACS) / E-3A Association of NATO in Geilenkirchen (2001–2004). From 2004 to 2014 he worked in the clinic and polyclinic for urology, pediatric urology and andrology at the Justus Liebig University in Giessen ( Wolfgang Weidner ). Bschleipfer was recognized as a specialist in urology in 2008. In 2009, the European Board of Urology (EBU) awarded him the title “Fellow of the European Board of Urology” (FEBU). In 2010, Bschleipfer was appointed senior physician at the clinic and was head of the urodynamics and neurourology section. Bschleipfer completed his habilitation in 2014 on the subject of "The overactive bladder - cholinergic systems of urinary bladder sensors ". He received the Venia legendi and the academic title “Dr. med. habil. ”and“ Privatdozent ”. In 2016 he was appointed professor at the Justus Liebig University in Giessen. Since 2014, Bschleipfer has been chief physician at the Clinic for Urology, Andrology and Pediatric Urology at the Klinikum Weiden / Kliniken Nordoberpfalz AG. It has the following additional medical designations: ' Naturopathic Treatment ' (2004), 'Emergency Medicine' (2006), 'Medicinal Tumor Therapy' (2010) and 'Andrology' (2010).

Scientific contribution

Bschleipfer began his scientific career in the field of urological traumatology . As part of his medical doctorate, he dealt with the biomechanics and trauma behavior of kidneys after blunt injuries. His work was able to demonstrate a gradual addition of different types of lesions at critical energy and decompensation limits with progressively increasing stress . This showed a significantly increased trauma susceptibility to organs with restricted drainage. A direct comparison of macroscopy and contrast agent computed tomography showed a very high level of diagnostic accuracy for the sectional image method. In the following, Bschleipfer dealt with functional urology, especially with the clinical picture of the overactive bladder (OAB). Bschleipfer's research focus was on the cholinergic system of urinary bladder sensors. Different muscarinic and nicotinic receptor subtypes and subunits could be identified on the afferents of the urinary bladder. Changes could also be shown which arise after obstruction of the bladder outlet, such as an enlarged prostate in the aging man. In addition, Bschleipfer's research was able to show a non-neuronal cholinergic system within the urothelium (bladder mucous membrane), which also expresses cholinergic receptors, does not differ between men and women and shows no significant changes in the presence of a bladder outlet obstruction. Further work by Bschleipfer was able to demonstrate a significant influence of systemic arteriosclerosis on the development of detrusor overactivity (DHA) and thus on the clinical picture of the overactive bladder (OAB). Together with Wolfgang Kummer , Director of the Institute for Anatomy and Cell Biology at the Justus Liebig University in Giessen, Bschleipfer worked on the first description of the urethral brush cell, a taste cell in the urethra that could be detected not only in humans but also in numerous mammals . This chemosensory “guardian cell” is able to “taste” bitter substances and special molecules (quorum-sensing molecules, QSM) from bacteria (penetrating the body). This triggers a reflex contraction of the bladder, which leads to the elimination of potential pathogens.

To date, Bschleipfer has published more than 45 PubMed-listed publications, held more than 250 national and international lectures, organized several congresses and seminars and wrote numerous (teaching) book contributions. As a member and secretary of the Benign Prostatic Syndrome Working Group (AK BPS) of the German Society for Urology (DGU), he was significantly involved in the development of the S2e guideline "Therapy of Benign Prostatic Syndrome (BPS)" and is currently working on the guideline "Diagnostics of Benign Prostatic Syndrome (BPS) ". He is a member of the guideline commission of the working group for urogynecology and plastic pelvic floor reconstruction AGUB eV of the German Society for Gynecology and Obstetrics eV (DGGG) for the development of the guideline "Diagnostics and Therapy of Overactive Bladder in Women". He is also the guideline coordinator of the guideline "Diagnostics and Therapy of Interstitial Cystitis (IC / BPS)".

Bschleipfer works as a reviewer for numerous scientific journals. These include:

  • European Urology (Eur Urol)
  • European Urology Focus (Eur Urol Focus)
  • British Journal of Urology (BJU Int)
  • European Journal of Obstetrics & Gynecology and Reproductive Biology (Eur J Obstet Gynecol Reprod Biol)
  • World Journal of Urology (World J Urol)
  • Life Sciences (Life Sci)
  • Neurourology and Urodynamics (Neurourol Urodyn)
  • Urologia internationalis (Urol Int)
  • Naunyn-Schmiedeberg's Archives of Pharmacology
  • Annals of Anatomy

Memberships in scientific associations (selection)

Bschleipfer is a member of various scientific associations. These include, among others:

  • European Association of Urology (EAU)
  • German Society for Urology (DGU)
  • Working group 'Benign Prostatic Syndrome' (BPS) of the German Society for Urology (DGU)
  • Working group 'Urological Functional Diagnostics and Urology of Women' of the German Society for Urology (DGU)
  • Forum Urodynamicum eV
  • Upper Palatinate Urologists eV
  • ICA Germany eV (member of the medical advisory board)

Honors and awards (selection)

  • Promotion of the Gifted by the State of Bavaria (1991)
  • Second Price Oral Presentation of the European Association of Urology (EAU) (2001)
  • Joseph Ströbl Award of the Joseph Ströbl Foundation in cooperation with the Technical University of Munich and the Ludwig Maximilians University of Munich (2001)
  • Sponsorship award from the Coordination Center for Clinical Studies (KKS) Marburg and the medical faculty of the Philipps University of Marburg (2006)
  • Research grant from the Forum Urodynamicum eV of the German Society for Urology (DGU) (2010)
  • Wolfgang Mauermayer Prize of the German Society for Urology (DGU) (2016)
  • FOCUS doctor list: Germany's top doctors in 2016 and 2017

Web links

Individual evidence

  1. ↑ a b Clinic for Urology, Andrology and Pediatric Urology. Kliniken Nordoberpfalz AG, accessed on July 10, 2017 .
  2. ↑ T. Bschleipfer (2007). Ethics of crisis medicine: Critical analysis of area-specific dilemmas: resource allocation, instrumentalisation and double loyalty. (opus4.kobv.de)
  3. ↑ a b T. Bschleipfer, K. Kornwachs: Military operational medicine - ethical dilemmas. In: Dtsch Arztebl. 107, 2010, pp. A-1448-A-1450.
  4. ↑ Professor title for urologists from Weiden. In: OberpfalzECHO. February 3, 2016, accessed July 10, 2017 .
  5. ↑ T. Bschleipfer, D. Kallieris, EW Hauck, W. Weidner, RA Pust: Blunt renal trauma: biomechanics and origination of renal lesions. In: Eur Urol. 42, 2002, pp. 614-621.
  6. ↑ T. Bschleipfer, D. Kallieris, P. Hallscheidt, EW Hauck, W. Weidner, RA Pust: Validity of computerized tomography in blunt renal trauma. In: J Urol. 170, 2003, pp. 2475-2479.
  7. ↑ T. Bschleipfer, F. Wagenlehner, W. Weidner: Etiology and pathogenesis of overactive bladder. In: Urologe A. 50, 2011, pp. 477-480.
  8. ↑ T. Bschleipfer, FM car Lehner, G. Liidecke, A. Pilatz, W. Weidner: Overactive bladder in the elderly. In: Urologe A. 52, 2013, pp. 800-804.
  9. ↑ T. Bschleipfer, G. Ludecke, M. Durschnabel, FM Wagenlehner, W. Weidner, A. Pilatz: Auricular acupuncture in patients with detrusor overactivity: a pilot study. In: Urologe A. 53, 2014, pp. 1633–1638.
  10. ↑ R. Nandigama, I. Ibanez-Tallon, KS Lips, U. Schwantes, W. Kummer, T. Bschleipfer: Expression of nicotinic acetylcholine receptor subunit mRNA in mouse bladder afferent neurons. In: Neuroscience. 229, 2013, pp. 27-35.
  11. ↑ R. Nandigama, M. Bonitz, T. Papadakis, U. Schwantes, T. Bschleipfer, W. Kummer: Muscarinic acetylcholine receptor subtypes overexpressed by mouse bladder afferent neurons. In: Neuroscience. 168, 2010, pp. 842-850.
  12. ↑ T. Bschleipfer, R. Nandigama, S. Moeller, C. Illig, W. Weidner, W. Kummer: Bladder outlet obstruction influences mRNA expression of cholinergic receptors on sensory neurons in mice. In: Life Sci. 91, 2012, pp. 1077-1081.
  13. ↑ T. Bschleipfer, K. Schukowski, W. Weidner, SA Grando, U. Schwantes, W. Kummer, KS Lips: Expression and distribution of cholinergic receptors in the human urothelium. In: Life Sci. 80, 2007, pp. 2303-2307.
  14. ↑ KS Lips, J. Wunsch, S. Zarghooni, T. Bschleipfer, K. Schukowski, W. Weidner, I. Wessler, U. Schwantes, H. Koepsell, W. Kummer: Acetylcholine and molecular components of its synthesis and release machinery in the urothelium. In: Eur Urol. 51, 2007, pp. 1042-1053.
  15. ↑ T. Bschleipfer, W. Weidner, W. Kummer, KS Lips: Does bladder outlet obstruction alter the non-neuronal cholinergic system of the human urothelium? In: Life Sci. 91, 2012, pp. 1082-1086.
  16. ↑ T. Bschleipfer, AK Dannenmaier, C. Illig, M. Kreisel, S. Gattenlohner, AC Langheinrich, GA Krombach, W. Weidner, M. Kampschulte: Systemic atherosclerosis causes detrusor overactivity: functional and morphological changes in hyperlipoproteinemic apoE - / - LDLR - / - mice. In: J Urol. 193, 2015, pp. 345-351.
  17. ↑ K. Deckmann, K. Filipski, G. Krasteva-Christ, M. Fronius, M. Althaus, A. Rafiq, T. Papadakis, L. Renno, I. Jurastow, L. Wessels, M. Wolff, B. Schutz , E. Weihe, V. Chubanov, T. Gudermann, J. Klein, T. Bschleipfer, W. Kummer: Bitter triggers acetylcholine release from polymodal urethral chemosensory cells and bladder reflexes. In: Proc Natl Acad Sci US A. 2014.
  18. ↑ Research team discovers "guardian cell" in the urinary tract, tiny cell as a big find. Oberpfalz Medien, February 20, 2017, accessed on July 10, 2017 .
  19. ↑ K. Deckmann, G. Krasteva-Christ, A. Rafiq, C. Herden, J. Wichmann, S. Knauf, C. Nassenstein, CG Grevelding, A. Dorresteijn, V. Chubanov, T. Gudermann, T. Bschleipfer, W. Kummer: Cholinergic urethral brush cells are widespread throughout placental mammals. In: Int Immunopharmacol. 29, 2015, pp. 51-56.
  20. ↑ T. Bschleipfer, T. Bach, R. Berges, K. Dreikorn, C. Gratzke, S. Madersbacher, MS Michel, R. Muschter, M. Oelke, O. Reich, C. Tschuschke, K. Höfner: S2e guideline of the German urologists: Instrumental treatment of benign prostatic hyperplasia. In: Urologe A. 55, 2016, pp. 195–207.
  21. ↑ K. Höfner, T. Bach, R. Berges, K. Dreikorn, C. Gratzke, S. Madersbacher, MS Michel, R. Muschter, M. Oelke, O. Reich, C. Tschuschke, T. Bschleipfer: S2e guideline of the German urologists: Conservative and pharmacologic treatment of benign prostatic hyperplasia. In: Urologe A. 55, 2016, pp. 184–194.
  22. ↑ Benign Prostatic Syndrome Working Group (AK BPS), German Society for Urology eV, Professional Association of German Urologists: S2e Guideline - Therapy of Benign Prostatic Syndrome (BPS). BoD - Books on Demand, Norderstedt 2014, p. 650.
  23. ↑ Gießen urologist receives Wolfgang Mauermayer Prize. Justus Liebig University Giessen, accessed on July 10, 2017 .
  24. ↑ Three chief physicians are represented in the nationwide “Focus” list. Kliniken Nordoberpfalz, accessed on July 26, 2017 .
personal data
SURNAME Bschleipfer, Thomas
BRIEF DESCRIPTION German medic and philosopher
DATE OF BIRTH January 26, 1972
PLACE OF BIRTH augsburg