Thomas Cremer (medical doctor)

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Thomas Cremer

Thomas Cremer (born July 7, 1945 in Miesbach ) is a German physician and professor at the Ludwig Maximilians University in Munich .

Thomas Cremer is the son of Hubert Cremer and brother of Christoph Cremer . He studied medicine at the Albert-Ludwigs-Universität Freiburg with his doctorate in 1973 as Dr. med. In 1971 he was at the Max Planck Institute for Experimental Medicine in Göttingen and from 1972 to 1978 at the Institute for Anthropology and Human Genetics at the University of Freiburg. From 1978 he was at the University of Heidelberg , where he completed his habilitation in 1983. In 1996 he became professor for anthropology and human genetics at the University of Munich.

In 1978 he was at the University of California, Irvine (with Michael W. Berns ), from 1986 to 1988 at Yale University (with Laura Manuelidis and David C. Ward ) and from 1989 to 1990 at Washington University with Maynard Olson .

He dealt with laser UV micro-irradiation of cell nuclei of eukaryotes (in vivo, developed with his brother Christoph Cremer) to determine the chromosome arrangement and developed molecular-cytogenetic methods (interphase cytogenetics, comparative genomic hybridization, chromosomal in-situ suppression Hybridization (Chromosome Painting) with Peter Lichter ). Since the mid-1990s, he has been concerned with the determination of the three-dimensional arrangement of cell nucleus components (such as genes and territories on chromosomes), their function in the cell (role in epigenetics and cell-typical gene expression) and evolutionary conservative structures in the cell nucleus as well as species and cell-typical structures Special features of these structures. He demonstrated that the arrangement of the chromosomes in the cell nucleus (also in the interphase between cell divisions) are not random and also differ depending on the cell type. He was also able to confirm the hypothesis of the chromosome territories of Carl Rabl and Theodor Boveri .

In 2009 he received the Schleiden Medal and he received the Maffo Vialli International Award for Histochemistry. He is a member of the Leopoldina (2006) and a corresponding member of the Heidelberg Academy of Sciences (2000). The German Society for Human Genetics awarded him the GfH Medal of Honor in 2011 for his services to human genetics in Germany .

Web links

Individual evidence

  1. idw, 2009
  2. ^ Member entry by Thomas Cremer (with picture) at the German Academy of Natural Scientists Leopoldina , accessed on September 19, 2016.
  3. Thomas Cremer. Member entry at the Heidelberg Academy of Sciences , accessed on September 19, 2016 .