Peter lights
Peter Lichter (born October 16, 1957 in Mannheim ) is a German biologist and university professor .
Career and areas of work
Lichter studied biology at Heidelberg University from 1977 to 1983 . He wrote his dissertation Structure and Expression of Genomic Information for the Heavy Chain of a Human Myosin , on which he received his doctorate in 1986 , at the Max Planck Institute for Medical Research in Heidelberg . Afterwards, Lichter was employed as a post-doctoral student at the School of Medicine in Yale (USA) for four years . In 1990 he went back to Heidelberg to the German Cancer Research Center (DKFZ), where he became head of the project group “Organization of Complex Genomes”. In 1992 he was at the DKFZ department managers and 1995 he was at the University of Heidelberg habilitation . He received the Venia legendi for Molecular Human Genetics . In 2000, Lichter became a full professor at Heidelberg University .
Lichter's fields of work include the pathomechanisms of tumor development, tumor markers , the molecular characterization of tumor cells and their genome organization and gene functions. He works on in situ hybridization methods for gene localization, on high-resolution mapping of chromosomal aberrations and on gene mapping. His specialty is leukemia , especially chronic lymphocytic leukemia , in which, among other things, he mapped genetic changes. Lichter made significant contributions to the first representations of individual human chromosomes in metaphase spreading and in the cell nuclei. To do this, he used chromosome-specific probes for fluorescence in situ hybridization .
Awards and memberships
- 2015 Johann Georg Zimmermann Medal
- 2012 Jacob Henle Medal
- 2004 Member of the German Academy of Sciences Leopoldina
- 2003 German Cancer Aid Prize
- 2002 German Cancer Prize together with Klaus-Michael Debatin
Publications (selection)
- D. Mertens, S. Wolf, C. Tschuch, C. Mund, D. Kienle, S. Ohl, P. Schroeter, F. Lyko, H. Döhner, S. Stilgenbauer, P. Lichter: Allelic silencing at the tumor- suppressor locus 13q14.3 suggests an epigenetic tumor-suppressor mechanism. In: Proceedings of the National Academy of Sciences . Volume 103, Number 20, May 2006, pp. 7741-7746, ISSN 0027-8424 . doi: 10.1073 / pnas.0600494103 . PMID 16684883 . PMC 1472515 (free full text).
- SM Görisch, M. Wachsmuth, C. Ittrich, CP Bacher, K. Rippe, P. Lichter: Nuclear body movement is determined by chromatin accessibility and dynamics. In: Proceedings of the National Academy of Sciences . Volume 101, Number 36, September 2004, pp. 13221-13226, ISSN 0027-8424 . doi: 10.1073 / pnas.0402958101 . PMID 15331777 . PMC 516551 (free full text).
- H. Döhner, S. Stilgenbauer, A. Benner, E. Leupolt, A. Kröber, L. Bullinger, K. Döhner, M. Bentz, P. Lichter: Genomic aberrations and survival in chronic lymphocytic leukemia. In: New England Journal of Medicine . Volume 343, Number 26, December 2000, pp. 1910-1916, ISSN 0028-4793 . doi: 10.1056 / NEJM200012283432602 . PMID 11136261 .
- P. Lichter, CJ Tang, K. Call, G. Hermanson, GA Evans, D. Housman, DC Ward: High-resolution mapping of human chromosome 11 by in situ hybridization with cosmid clones. In: Science . Volume 247, Number 4938, January 1990, pp. 64-69, ISSN 0036-8075 . PMID 2294592 .
Web links
- Department of Molecular Genetics - Prof. Dr. Peter Lichter website at the DKFZ
- spos, bak: Genetic research with morals - Peter Lichter is part of the puzzle. In: ruprecht - Heidelberg student newspaper. Number 67, July 2000, p. 3.
Individual evidence
- ^ A b German Academy of Sciences Leopoldina - Newly elected members 2004. (PDF; 1.7 MB) p. 50.
- ↑ Prof. Dr. Peter lights. ( Page no longer available , search in web archives ) Info: The link was automatically marked as defective. Please check the link according to the instructions and then remove this notice. (PDF; 27 kB) CV (English)
- ↑ P. Lichter, T. Cremer, J. Borden, L. Manuelidis, DC Ward: Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries. In: Human genetics. Volume 80, Number 3, November 1988, pp. 224-234, ISSN 0340-6717 . PMID 3192212 .
- ↑ T. Cremer, P. Lichter, J. Borden, DC Ward, L. Manuelidis: Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes. In: Human genetics. Volume 80, Number 3, November 1988, pp. 235-246, ISSN 0340-6717 . PMID 3192213 .
- ↑ Member entry by Peter Lichter (with picture and CV) at the German Academy of Natural Scientists Leopoldina , accessed on July 17, 2016.
personal data | |
---|---|
SURNAME | Lights, Peter |
BRIEF DESCRIPTION | German biologist and university professor |
DATE OF BIRTH | October 16, 1957 |
PLACE OF BIRTH | Mannheim |