Toltrazuril
| Structural formula | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|||||||||||||||||||
| General | |||||||||||||||||||
| Non-proprietary name | Toltrazuril | ||||||||||||||||||
| other names |
1-methyl-3- (3-methyl-4- {4 - [(trifluoromethyl) thio] phenoxy} phenyl) -1,3,5-triazine-2,4,6 (1 H , 3 H , 5 H ) -trion |
||||||||||||||||||
| Molecular formula | C 18 H 14 F 3 N 3 O 4 S | ||||||||||||||||||
| External identifiers / databases | |||||||||||||||||||
|
|||||||||||||||||||
| Drug information | |||||||||||||||||||
| ATC code | |||||||||||||||||||
| Drug class |
Antiparasitic (Antiprotozoic) |
||||||||||||||||||
| properties | |||||||||||||||||||
| Molar mass | 425.38 g mol −1 | ||||||||||||||||||
| safety instructions | |||||||||||||||||||
|
|||||||||||||||||||
| As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . | |||||||||||||||||||
Toltrazuril is a drug from the group of triazine derivatives that is used against protozoal infections ( coccidiosis , toxoplasmosis , sarcocystosis ) in veterinary medicine in both mammals and birds .
Toltrazuril is effective against all coccidia (including Toxoplasma gondii and Sarcocystis ) studied to date . It inhibits the respiratory chain and the pyrimidine synthesis in the parasites and thus the development of the first and second generation of schizonts . It is not effective against free sporozoites and merozoites . The active ingredient does not prevent the animal from developing an immunity to coccidia.
The active ingredient must not be used in lactating cows , chickens whose eggs are intended for human consumption, and pregnant rabbits . When hedgehog oral administration can mucosa cause irritation.
Trade names
Baycox , Dozuril , Toltranil , Zuritol
Individual evidence
- ↑ a b Datasheet Toltrazuril from Sigma-Aldrich , accessed on May 15, 2017 ( PDF ).
Web links
- Entry on Toltrurazil at Vetpharm, accessed on August 11, 2012.
