UDP-glucose pyrophosphorylase
UDP-glucose pyrophosphorylase | ||
---|---|---|
UDP-glucose pyrophosphorylase octamer, human according to PDB 4R7P | ||
Properties of human protein | ||
Mass / length primary structure | 507 amino acids | |
Secondary to quaternary structure | Homooctamer | |
Isoforms | 2 | |
Identifier | ||
Gene name | UGP2 | |
External IDs | ||
Enzyme classification | ||
EC, category | 2.7.7.9 , nucleotidyl transferase | |
Response type | Transmission of UDP | |
Substrate | α-D-glucose-1-phosphate + UTP | |
Products | UDP-glucose + pyrophosphate | |
Occurrence | ||
Parent taxon | Creature |
UDP-glucose pyrophosphorylase (UGPase) (or UTP-glucose-1-phosphate-uridylyl transferase , gene : UGP2 ) is the name of the enzyme that catalyzes the conversion of UTP and glucose-1-phosphate to UDP-glucose . This reaction is part of several metabolic pathways in most living things. The previously suspected second homolog in humans with the gene UGP1 probably does not exist.
Catalyzed reaction
UMP is transferred from UTP to glucose-1-phosphate, resulting in UDP-glucose and pyrophosphate. The reaction is part of glycogen synthesis , glycogen breakdown , galactose metabolism and uronic acid metabolism.
Individual evidence
Web links
Wikibooks: Biochemistry and Pathobiochemistry: Glycogen Synthesis - Learning and Teaching Materials
Wikibooks: Biochemistry and Pathobiochemistry: Galactose Metabolism - Learning and Teaching Materials
Wikibooks: Biochemistry and Pathobiochemistry: Uronic Acid Metabolism - Learning and Teaching Materials