Ulrich Laemmli

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Ulrich Karl Laemmli , actually Lämmli, (* 1940 in Schaffhausen ) is a Swiss biochemist , molecular biologist and professor at the University of Geneva . He is known for developing the SDS-PAGE .

Laemmli studied physics at the ETH Zurich and received a doctorate in molecular biology from the University of Geneva. He was a professor at Princeton University and has been at Geneva University since 1981.

Laemmli succeeded in significantly improving polyacrylamide gel electrophoresis for the separation of proteins. He published it in a Nature article in 1970, which was actually devoted to the structure of a bacteriophage and is one of the most cited scientific papers of all. Laemmli developed the method during a stay abroad in Cambridge, but did not patent it.

He also looked at the structure of chromatin .

In 1988 he received the Marcel Benoist Prize and in 1996 the Louis Jeantet Prize . Since 1989 he has been a member of the Academia Europaea . In 2006 he was elected a Fellow of the American Association for the Advancement of Science .

Fonts

  • Cleavage of structural proteins during the assembly of the head of bacteriophage T4. In: Nature . Volume 227, 1970, pp. 680-685.
  • with DW Cleveland, SG Fischer, MW Kirschner: Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. In: Journal of Biological Chemistry . Volume 252, 1977, pp. 1102-1106.

Web links

Individual evidence

  1. Cited over 213,005 times by 2014 and is in second place after a work by Oliver Lowry from 1951. Cf. Nature article The top 100 papers and interview with Ulrich Laemmli. In: NZZ Folio . 2005.
  2. ↑ Directory of members: Ulrich Laemmli. Academia Europaea, accessed on August 10, 2017 .
  3. Fellows of the AAAS: UK Laemmli. (No longer available online.) American Association for the Advancement of Science, archived from the original on January 31, 2018 ; accessed on January 31, 2018 . Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. @1@ 2Template: Webachiv / IABot / www.aaas.org