Vladimir Petrovich Demichow
Vladimir Petrovich Demichow ( Russian Владимир Петрович Демихов ; born July 18, 1916 in Kulini , today Volgograd Oblast ; † November 22, 1998 in Moscow ) was a Russian surgeon and pioneer of transplant surgery . He was particularly known for his experiments on dogs.
His work
Between 1930 and 1950 experimented with Demichow he invented artificial heart , bypass surgery and transplants of the heart and lungs . Among other things, he performed the first heart transplant in a warm-blooded animal , the first lung transplant and the first heart-lung transplant in the history of surgery. He was best known in public through operations in which he transplanted heads and fore bodies. His experiments were referred to in the Soviet Union as the " Sputnik of surgery".
Demichow's dissertation with the title "Experimental transplantation of vital organs" was published in 1960 and in 1962 was also published outside the Soviet Union . For a long time it was the only monograph on organ and tissue transplants. The South African heart surgeon Christiaan Barnard , who performed the first successful heart transplant on a human in 1967, visited Demichow's laboratory in 1960 and 1963. He regarded Demichow as his teacher.
During his experiments, Demichow erroneously assumed that the failure of donor organs was not caused by immune reactions but by inadequate surgical techniques. Based on this hypothesis , he developed 24 different surgical techniques for heart transplants on around 250 animals. In one dog, a postoperative survival time of 32 days was achieved.
Demichow died unnoticed in 1998, but shortly before his death received the medal “ For Merit to the Fatherland ”.
Publications
- Demikhov, VP Experimental transplantation of vital organs. Authorized translation from the Russian by Basil Haigh./ New York: Consultant's Bureau, 1962
literature
- A. Rukosujew and others: Demichow, WP: Significance of his experimental activity in the development of organ transplantation. In: The Thoracic and cardiovascular surgeon 56, 2008, pp. 317-322. PMID 18704852
- DKC Cooper: Vladimir Demikhov. In: Ann Thorac Surg 59, 1995, p. 1628. PMID 7771869
- IE Konstantinov: A Mystery of Vladimir P. Demikhov: The 50th Anniversary of the First Intrathoracic Transplantation. In: Ann Thorac Surg 65, 1998, pp. 1171-1177. PMID 9564962
- HB Shumacker: A surgeon to remember: notes about Vladimir Demikhov In: The Annals of Thoracic Surgery 58, 1994, pp. 1196-1198. PMID 7944786
- Anonymous: Vladimir Petrovich Demikhov. In: J Heart Transplant 8, 1989, pp. 427-429. PMID 2693661
Individual evidence
- ↑ B. Ertl. Coronary transplant vasculopathy after heart transplantation depending on the immunosuppressive therapy regimen. (PDF; 1.4 MB) Dissertation, Ludwig Maximilians University Munich, 2007
- ↑ B. Reichart Heart and Heart Lung Transplantation on the Way to the Method. Verlag RS Schulz, 1987 ISBN 3-7962-0155-5
Web links
personal data | |
---|---|
SURNAME | Demichow, Vladimir Petrovich |
ALTERNATIVE NAMES | Демихов, Владимир Петрович (Russian spelling) |
BRIEF DESCRIPTION | Russian pioneer of transplant surgery |
DATE OF BIRTH | July 18, 1916 |
PLACE OF BIRTH | Kulini , Russian Empire |
DATE OF DEATH | November 22, 1998 |
Place of death | Moscow , Russia |