Center for Molecular Neurobiology Hamburg
The Center for Molecular Neurobiology Hamburg (ZMNH) is a neuroscientific research institution founded in 1987 in the Medical Faculty of the University of Hamburg at the University Medical Center Hamburg-Eppendorf (UKE).
organization
The ZMNH comprises five institutes, eight independent research groups, three guest groups, an emeritus group and five scientific service facilities (as of 2020). Approx. 190 employees work in the center.
Fundamental decisions are made by the college, in which the institute directors, the managing director and one representative each of the research group leaders and scientists are represented. It elects the director of the center from among the institute directors.
The scientific advisory board advises the UKE on the scientific and strategic orientation of the ZMNH and evaluates its scientific work.
history
From 1986 the ZMNH was implemented on the basis of an agreement between the University of Hamburg, the citizens of the Free and Hanseatic City of Hamburg and the third-party funder, the Federal Ministry for Research and Technology . The federal government took over the costs of the research groups and the scientific service facilities as part of a 10-year start-up financing. In 1988 the center was able to begin its work with five research groups, initially in interim buildings. The founding phase of the ZMNH and the work of the founding director, Dietmar Richter, ended with the move to a new building in Martinistraße / corner of Falkenried in 1996 .
Institutes and research groups
- Institute for Medical Systems Biology (founded in 2017; Director: Stefan Bonn): Integration and analysis of biomedical data to research biomarkers , disease mechanisms and therapeutic approaches.
- Institute of Neuroimmunology and Multiple Sclerosis (founded 2006; Director: Manuel Friese): basic research and its translation into human use for disease development and treatment of multiple sclerosis and other diseases of the nervous system caused by immunological trigger processes or maintained.
- Institute for Synaptic Physiology (founded in 2011; Director: Thomas Oertner ): Analysis of the transmission of information at individual synapses using high-resolution microscopy .
- Institute for Molecular Neurogenetics (founded in 2010; Director: Matthias Kneussel ): Molecular mechanisms of neuronal transport processes in the context of synaptic plasticity , learning and memory.
- Institute for Molecular and Cellular Cognition (founded in 2008; Director: Dietmar Kuhl ): Genes that control synaptic plasticity in the mammalian brain and the role of their expression and regulation for memory development and mental illness .
- Founding institute
- Institute for Cell Biochemistry and Clinical Neurobiology (Director: Dietmar Richter )
- Research groups
- Synaptic information processing (founded in 2017; head: Simon Wiegert): decoding of synaptic coding and storage of information and memory contents in the brain.
- Neuronal protein transport (founded in 2015; head: Marina Mikhaylova): Investigations into the molecular and cellular mechanisms of clustered plasticity in dendritic segments.
- Molecular and cellular signal transduction (founded in 2015; Head: Meliha Karsak): Biochemical and pharmacological studies of membrane receptors, especially of the cannabinoid system , their signaling and function in physiological and pathological states of the nervous system and other organs.
- Behavioral biology (founded in 2013; head: Fabio Morellini): behavioral analyzes to understand both the adaptive capacity of the intact organism and to investigate the effects of certain genetic or neuroendocrinological manipulations.
- Neural development (founded in 2012; head: Froylan Calderón de Anda): In vivo studies on the mechanisms of the development of axons and dendrites of neuronal cells with regard to their functional importance.
- Neural Development and Connectivity (founded in 2011; Head: Peter Soba): Molecular Mechanisms of Building Neural Networks .
- Neuronal translational control (founded in 2010; Head: Kent Duncan): Molecular mechanisms and the functional importance of the regulation of protein synthesis in the nervous system.
- Developmental Neurophysiology (founded in 2008; Head: Ileana Hanganu-Opatz): Electrophysiological studies on the formation, function and modulation of early neural networks on the mouse model .
- Guest groups
- Dendritic organelles and synapse function (founded in 2015; head: Michael Kreutz): Micro-secretory systems in dendrites and their influence on synaptic plasticity.
- Experimental neuropediatrics (founded in 2009, guest group since 2013; head: Axel Neu): Molecular, cellular and systemic changes that are triggered by pathological activation of neuronal networks in the cortex and hippocampus of transgenic mouse models.
- Fraunhofer IME ScreeningPort (Head: Ole Pless): Identification and validation of biomarkers for neurodegeneration based on proteins, small non-coding RNAs and metabolites in patient samples.
- Emeritus group
- Biosynthesis of neural structures (Head: Melitta Schachner Carmartine ): Function of cell recognition molecules in the extracellular matrix and on the cell surface for the development of the nervous system, synaptic plasticity and its regeneration after injuries.
Web links
- Center for Molecular Neurobiology Hamburg (ZMNH)
- Teaching at the ZMNH
Coordinates: 53 ° 35 ′ 12 " N , 9 ° 58 ′ 15.9" E