SLC13A2: Difference between revisions

SLC13A2
Identifiers
Aliases	SLC13A2, NADC1, NaCT, NaDC-1, SDCT1, solute carrier family 13 member 2
External IDs	OMIM: 604148 MGI: 1276558 HomoloGene: 2965 GeneCards: SLC13A2
Gene location (Human)
Chr.	Chromosome 17 (human)
End	28,497,781 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	78,313,043 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; duodenum; ; kidney; ; salivary gland; ; minor salivary glands; ; lactiferous duct; ; parotid gland; ; gallbladder; ; rectum; ; trachea;
	Top expressed in
	intestinal villus; ; jejunum; ; left colon; ; proximal tubule; ; ileum; ; kidney; ; conjunctival fornix; ; morula; ; seminal vesicula; ; crypt of lieberkuhn of small intestine;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	low-affinity sodium:dicarboxylate symporter activity; symporter activity; transporter activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; extracellular exosome; membrane;
Biological process	ion transport; sodium ion transport; dicarboxylic acid transport; transmembrane transport; anion transmembrane transport; transport;
	Sources:Amigo / QuickGO
Orthologs
	9058
	20500
	ENSG00000007216
	ENSMUSG00000001095
	Q13183
	Q9ES88
	NM_001145975; NM_001145976; NM_003984; NM_001346683; NM_001346684
	NM_022411
	NP_001139447; NP_001333612; NP_001333613; NP_003975
	NP_071856
	Wikidata
View/Edit Human	View/Edit Mouse

Browse history interactively

← Previous edit

Content deleted Content added

VisualWikitext

Inline

Latest revision as of 02:33, 29 November 2023

Solute carrier family 13 member 2 is a protein that is encoded in humans by the SLC13A2 gene.^[5]^[6]^[7]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000007216 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000001095 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Pajor AM (Dec 1996). "Molecular cloning and functional expression of a sodium-dicarboxylate cotransporter from human kidney". Am J Physiol. 270 (4 Pt 2): F642–8. doi:10.1152/ajprenal.1996.270.4.F642. PMID 8967342.
^ Mann SS, Hart TC, Pettenati MJ, von Kap-herr C, Holmes RP (Jun 1999). "Assignment of the sodium-dependent dicarboxylate transporter gene (SLC13A2 alias NaDC-1) to human chromosome region 17p11.1→q11.1 by radiation hybrid mapping and fluorescence in situ hybridization". Cytogenet Cell Genet. 84 (1–2): 89–90. doi:10.1159/000015222. PMID 10343111. S2CID 26457719.
^ "Entrez Gene: SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2".

Further reading[edit]

Inoue K, Zhuang L, Ganapathy V (2003). "Human Na+ -coupled citrate transporter: primary structure, genomic organization, and transport function". Biochem. Biophys. Res. Commun. 299 (3): 465–71. doi:10.1016/S0006-291X(02)02669-4. PMID 12445824.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Bai X, Chen X, Fen Z, et al. (2005). "Expression of EGFP/SDCT1 fusion protein, subcellular localization signal analysis, tissue distribution and electrophysiological function study". Science in China Series C: Life Sciences. 47 (6): 530–9. doi:10.1360/03yc0044. PMID 15620109. S2CID 36487757.
Pajor AM, Randolph KM (2005). "Conformationally sensitive residues in extracellular loop 5 of the Na+/dicarboxylate co-transporter". J. Biol. Chem. 280 (19): 18728–35. doi:10.1074/jbc.M501265200. PMC 1224748. PMID 15774465.
Okamoto N, Aruga S, Matsuzaki S, et al. (2007). "Associations between renal sodium-citrate cotransporter (hNaDC-1) gene polymorphism and urinary citrate excretion in recurrent renal calcium stone formers and normal controls". Int. J. Urol. 14 (4): 344–9. doi:10.1111/j.1442-2042.2007.01554.x. PMID 17470169. S2CID 41274929.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000007216 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000001095 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8967342-5] Pajor AM (Dec 1996). "Molecular cloning and functional expression of a sodium-dicarboxylate cotransporter from human kidney". Am J Physiol. 270 (4 Pt 2): F642–8. doi:10.1152/ajprenal.1996.270.4.F642. PMID 8967342.

[pmid10343111-6] Mann SS, Hart TC, Pettenati MJ, von Kap-herr C, Holmes RP (Jun 1999). "Assignment of the sodium-dependent dicarboxylate transporter gene (SLC13A2 alias NaDC-1) to human chromosome region 17p11.1→q11.1 by radiation hybrid mapping and fluorescence in situ hybridization". Cytogenet Cell Genet. 84 (1–2): 89–90. doi:10.1159/000015222. PMID 10343111. S2CID 26457719.

[entrez-7] "Entrez Gene: SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2".

[1]

[2]

[3]

[4]

[5]

[6]

[7]

@@ Line 1: / Line 1: @@
+{{Short description|Protein-coding gene in the species Homo sapiens}}
 {{Infobox_gene}}
-'''Solute carrier family 13 member 2''' is a [[protein]] that is encoded in humans by the ''SLC13A2'' [[gene]].<ref name="pmid8967342">{{cite journal | author = Pajor AM | title = Molecular cloning and functional expression of a sodium-dicarboxylate cotransporter from human kidney | journal = Am J Physiol | volume = 270 | issue = 4 Pt 2 | pages = F642–8 |date=Dec 1996 | pmid = 8967342 | pmc =  | doi =  }}</ref><ref name="pmid10343111">{{cite journal | vauthors = Mann SS, Hart TC, Pettenati MJ, von Kap-herr C, Holmes RP | title = Assignment of the sodium-dependent dicarboxylate transporter gene (SLC13A2 alias NaDC-1) to human chromosome region 17p11.1→q11.1 by radiation hybrid mapping and fluorescence in situ hybridization | journal = Cytogenet Cell Genet | volume = 84 | issue = 1-2 | pages = 89–90 |date=Jun 1999 | pmid = 10343111 | pmc =  | doi =10.1159/000015222  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9058| accessdate = }}</ref>
+'''Solute carrier family 13 member 2''' is a [[protein]] that is encoded in humans by the ''SLC13A2'' [[gene]].<ref name="pmid8967342">{{cite journal | author = Pajor AM | title = Molecular cloning and functional expression of a sodium-dicarboxylate cotransporter from human kidney | journal = Am J Physiol | volume = 270 | issue = 4 Pt 2 | pages = F642–8 |date=Dec 1996 | pmid = 8967342 | doi =  10.1152/ajprenal.1996.270.4.F642}}</ref><ref name="pmid10343111">{{cite journal | vauthors = Mann SS, Hart TC, Pettenati MJ, von Kap-herr C, Holmes RP | title = Assignment of the sodium-dependent dicarboxylate transporter gene (SLC13A2 alias NaDC-1) to human chromosome region 17p11.1→q11.1 by radiation hybrid mapping and fluorescence in situ hybridization | journal = Cytogenet Cell Genet | volume = 84 | issue = 1–2 | pages = 89–90 |date=Jun 1999 | pmid = 10343111 | doi =10.1159/000015222  | s2cid = 26457719 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9058}}</ref>
 ==References==
@@ Line 8: / Line 9: @@
 {{refbegin | 2}}
 *{{cite journal  | vauthors=Inoue K, Zhuang L, Ganapathy V |title=Human Na+ -coupled citrate transporter: primary structure, genomic organization, and transport function. |journal=Biochem. Biophys. Res. Commun. |volume=299 |issue= 3 |pages= 465–71 |year= 2003 |pmid= 12445824 |doi=10.1016/S0006-291X(02)02669-4  }}
-*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
-*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |doi-access= free }}
 *{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal   |vauthors=Bai X, Chen X, Fen Z, etal |title=Expression of EGFP/SDCT1 fusion protein, subcellular localization signal analysis, tissue distribution and electrophysiological function study. |journal=Science in China Series C: Life Sciences |volume=47 |issue= 6 |pages= 530–9 |year= 2005 |pmid= 15620109 |doi=  10.1360/03yc0044}}
+*{{cite journal   |vauthors=Bai X, Chen X, Fen Z, etal |title=Expression of EGFP/SDCT1 fusion protein, subcellular localization signal analysis, tissue distribution and electrophysiological function study. |journal=Science in China Series C: Life Sciences |volume=47 |issue= 6 |pages= 530–9 |year= 2005 |pmid= 15620109 |doi=  10.1360/03yc0044|s2cid=36487757 }}
-*{{cite journal  | vauthors=Pajor AM, Randolph KM |title=Conformationally sensitive residues in extracellular loop 5 of the Na+/dicarboxylate co-transporter. |journal=J. Biol. Chem. |volume=280 |issue= 19 |pages= 18728–35 |year= 2005 |pmid= 15774465 |doi= 10.1074/jbc.M501265200  | pmc=1224748 }}
+*{{cite journal  | vauthors=Pajor AM, Randolph KM |title=Conformationally sensitive residues in extracellular loop 5 of the Na+/dicarboxylate co-transporter. |journal=J. Biol. Chem. |volume=280 |issue= 19 |pages= 18728–35 |year= 2005 |pmid= 15774465 |doi= 10.1074/jbc.M501265200  | pmc=1224748 |doi-access=free }}
-*{{cite journal   |vauthors=Okamoto N, Aruga S, Matsuzaki S, etal |title=Associations between renal sodium-citrate cotransporter (hNaDC-1) gene polymorphism and urinary citrate excretion in recurrent renal calcium stone formers and normal controls. |journal=Int. J. Urol. |volume=14 |issue= 4 |pages= 344–9 |year= 2007 |pmid= 17470169 |doi= 10.1111/j.1442-2042.2007.01554.x }}
+*{{cite journal   |vauthors=Okamoto N, Aruga S, Matsuzaki S, etal |title=Associations between renal sodium-citrate cotransporter (hNaDC-1) gene polymorphism and urinary citrate excretion in recurrent renal calcium stone formers and normal controls. |journal=Int. J. Urol. |volume=14 |issue= 4 |pages= 344–9 |year= 2007 |pmid= 17470169 |doi= 10.1111/j.1442-2042.2007.01554.x |s2cid=41274929 |doi-access= }}
 {{refend}}