Sodium/hydrogen exchanger 6

SLC9A6
Identifiers
Aliases	SLC9A6, MRSA, NHE6, solute carrier family 9 member A6, MRXSCH
External IDs	OMIM: 300231; MGI: 2443511; HomoloGene: 55971; GeneCards: SLC9A6; OMA:SLC9A6 - orthologs
Gene location (Human) Chr. X chromosome (human) Band Xq26.3 Start 135,973,841 bp End 136,047,269 bp
Gene location (Mouse) Chr. X chromosome (mouse) Band X|X A5- A6 Start 55,655,117 bp End 55,709,590 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in middle temporal gyrus pons postcentral gyrus superior vestibular nucleus orbitofrontal cortex superior frontal gyrus entorhinal cortex Brodmann area 46 Region I of hippocampus proper Brodmann area 23 Top expressed in superior cervical ganglion Region I of hippocampus proper dorsomedial hypothalamic nucleus substantia nigra ventral tegmental area otolith organ utricle ciliary body ventromedial nucleus superior colliculus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function solute:proton antiporter activity antiporter activity potassium:proton antiporter activity sodium:proton antiporter activity Cellular component axon terminus integral component of membrane recycling endosome endosome late endosome early endosome membrane endoplasmic reticulum membrane intracellular membrane-bounded organelle membrane axonal spine plasma membrane synapse recycling endosome membrane dendrite early endosome mitochondrion endosome membrane cytoplasmic vesicle Biological process neuron projection morphogenesis dendrite extension sodium ion transport proton transmembrane transport synapse organization cation transport ion transport brain-derived neurotrophic factor receptor signaling pathway dendritic spine development regulation of neurotrophin TRK receptor signaling pathway axon extension regulation of pH potassium ion transmembrane transport transmembrane transport regulation of intracellular pH sodium ion import across plasma membrane anion transmembrane transport sodium ion transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 10479 236794 Ensembl ENSG00000198689 ENSMUSG00000060681 UniProt Q92581 n/a RefSeq (mRNA) NM_001042537 NM_001177651 NM_006359 NM_001330652 NM_001379110 NM_001400909 NM_001400910 NM_001400911 NM_001400912 NM_001400913 NM_172780 NM_001358861 RefSeq (protein) NP_001036002 NP_001171122 NP_001317581 NP_006350 NP_001366039 n/a Location (UCSC) Chr X: 135.97 – 136.05 Mb Chr X: 55.66 – 55.71 Mb PubMed search
Wikidata
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Solute carrier family 9 (sodium/hydrogen exchanger), member 6, also known as SLC9A6, is a human gene.

See also

• SLC9A6+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.