Wikipedia:WikiProject Molecular Biology/Cell Signaling

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Key components of the MAPK/ERK pathway, by JWSchmidt.

Some Wikipedians have formed a project to better organize information in articles related to Cell Signaling. This page and its subpages contain their suggestions; it is hoped that this project will help to focus the efforts of other Wikipedians. If you would like to help, please inquire on the talk page and see the to-do list there.

For more information on WikiProjects, please see Wikipedia:WikiProject and Wikipedia:WikiProject/Best practices.

Title

WikiProject on Cell Signaling

Scope

This project is dedicated to improving and organising the Wikipedia articles on cell signaling to provide a convinient and reliable reference of the known signal transduction pathways. It covers the pathway pages and individual protein pages related to them.

Goals

  • Creating comprehensive articles for each known cell signaling pathway
  • Organising cell signaling articles with navigation boxes like these: Wikipedia:WikiProject Molecular and Cellular Biology#Protein topics navigation boxes.
  • Organising and creating articles on notable proteins involved in signaling pathways.
  • Providing each pathway with a clear diagram of its structure.
  • Clearly citing sources, especially for active research topics

Target audience

  • Introduction to pathway articles should make minimal use of jargon and be kept relatively simple
  • Subsections and protein pages can be more technical

Parentage

This is a daughter project of WikiProject Molecular and Cellular Biology

Similar WikiProjects

WikiProject Clinical medicine and WikiProject Drugs may be relevant to this project.

Participants

Name Talk page Special interests
Peter Znamenskiy Talk Cell culture and adult stem cells
Rockpocket Talk G-protein coupled receptors
David Iberri Talk Embryogenesis (especially nervous system development)
John Schmidt Talk illustrations
Gacggt Talk Skeletal Muscle biology, Akt pathway, NF-kappaB pathway, some GPCRs, Neurotrophins, MuSK, agrin, Neuromuscular junction, etc
Kohlasz Talk Chemotaxis
EquationDoc Talk Pathways involved in cancer prevention and formation
JE.at.UWO Talk Immunology, development, endocrinology and reproductive physiology.
Biochemza Talk Immunology, neutrophils, tyrosine kinase signaling, calcium signaling

Structure

Proposed structure of a pathway article:

  • General introduction - keep it simple and clear
  • History/Discovery - discovery, seminal papers
  • Mechanism - the proteins involved and how they interact.
  • Role - the role of the pathway
  • Human disease - alternatively this can be incorporated into the previous section
  • Current research - recent advances, future directions

For individual proteins, see suggestions in Wikipedia:WikiProject_Molecular_and_Cellular_Biology#Structures

Proposed scheme for pathway diagrams is described here. Please do comment and contribute.

Hierarchy definition

No classification of this project has been defined.

Projects

Tasks

Adopt an article

Similar to the Collaboration of the week, but on a smaller scale, you might want to "adopt" an article. This would involve doing the research, writing, and picture-taking (if possible) for either a non-existent article or a stub. Of course, everyone else can still edit an adopted article, and you can work on other things too, but the idea is to find a focus for a while, to try and build up the number of quality articles the Project has produced.

General strategy and discussion forums

Templates

Infoboxes

Other templates

{{Template:Cell Signaling Project}} Template:Cell Signaling Project

{{Template:Cell_signaling}}


{{Template:Lipid_signaling}}

{{Template:TGF beta signaling}}

Categories

Lists

Articles

Ligand (biochemistry)
Receptor (biochemistry)
Second messenger
Protein kinase
Transcription factor
PI3K
PTEN
Akt
PDK1
PDK2
SHIP2
PHLPP
Tsc
mTOR
p70S6K
4E-BP
GSK-3
Catenin
NFAT
FOXO
BAD
Bcl-2
Caspase
Calmodulin
Sonic Hedgehog
Smoothened
Diacylglycerol
Inositol triphosphate
Inositol triphosphate receptor
Phospholipase
STAT protein
JAK
Epidermal growth factor receptor
Ras
Raf
MAPK
Mitogen-activated protein kinase
Activin
Transforming growth factor
SMAD (protein)
R-SMAD
I-SMAD
Catenin
GSK-3

Archives

Sister Project links