Electrogenic sodium bicarbonate cotransporter 1

SLC4A4
Identifiers
Aliases	SLC4A4, HNBC1, KNBC, NBC1, NBC2, NBCe1-A, SLC4A5, hhNMC, pNBC, kNBC1, solute carrier family 4 member 4
External IDs	OMIM: 603345; MGI: 1927555; HomoloGene: 55776; GeneCards: SLC4A4; OMA:SLC4A4 - orthologs
Gene location (Human) Chr. Chromosome 4 (human) Band 4q13.3 Start 71,186,757 bp End 71,572,087 bp
Gene location (Mouse) Chr. Chromosome 5 (mouse) Band 5|5 E1 Start 89,034,345 bp End 89,387,512 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in jejunal mucosa external globus pallidus pancreatic ductal cell internal globus pallidus kidney tubule body of pancreas duodenum bronchial epithelial cell glomerulus Region I of hippocampus proper Top expressed in ciliary body cerebellar vermis kidney globus pallidus dorsal tegmental nucleus medial vestibular nucleus iris mammillary body ventral tegmental area medial geniculate nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transporter activity anion transmembrane transporter activity protein binding symporter activity inorganic anion exchanger activity sodium:bicarbonate symporter activity identical protein binding Cellular component integral component of membrane plasma membrane basolateral plasma membrane integral component of plasma membrane extracellular exosome membrane Biological process bicarbonate transport anion transmembrane transport anion transport sodium ion transport sodium ion transmembrane transport ion transport inorganic anion transport regulation of intracellular pH transmembrane transport transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8671 54403 Ensembl ENSG00000080493 ENSMUSG00000060961 UniProt Q9Y6R1 O88343 RefSeq (mRNA) NM_001098484 NM_001134742 NM_003759 NM_001136260 NM_001197147 NM_018760 NM_001359211 NM_001359212 NM_001359213 RefSeq (protein) NP_001091954 NP_001128214 NP_003750 NP_001129732 NP_001184076 NP_061230 NP_001346140 NP_001346141 NP_001346142 Location (UCSC) Chr 4: 71.19 – 71.57 Mb Chr 5: 89.03 – 89.39 Mb PubMed search
Wikidata
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Solute carrier family 4, sodium bicarbonate cotransporter, member 4, also known as SLC4A4, is a human gene.

See also

• Solute carrier family

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.