Vesicular glutamate transporter 1

SLC17A7
Identifiers
Aliases	SLC17A7, BNPI, VGLUT1, solute carrier family 17 member 7
External IDs	OMIM: 605208; MGI: 1920211; HomoloGene: 113454; GeneCards: SLC17A7; OMA:SLC17A7 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	49,442,360 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	44,825,566 bp
RNA expression pattern
	Top expressed in
	superior frontal gyrus; ; Brodmann area 10; ; frontal pole; ; Region I of hippocampus proper; ; middle temporal gyrus; ; Brodmann area 46; ; dorsolateral prefrontal cortex; ; orbitofrontal cortex; ; cingulate gyrus; ; postcentral gyrus;
	Top expressed in
	superior frontal gyrus; ; prefrontal cortex; ; piriform cortex; ; cerebellar cortex; ; hippocampus proper; ; primary motor cortex; ; subiculum; ; habenula; ; cerebellar vermis; ; amygdala;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	inorganic phosphate transmembrane transporter activity; sodium:inorganic phosphate symporter activity; extracellularly glutamate-gated chloride channel activity; symporter activity; L-glutamate transmembrane transporter activity; neurotransmitter transmembrane transporter activity;
Cellular component	postsynapse; integral component of membrane; membrane; synaptic vesicle; plasma membrane; synapse; excitatory synapse; synaptic vesicle membrane; cerebellar mossy fiber; presynaptic active zone; cell junction; intracellular organelle; neuron projection; clathrin-sculpted glutamate transport vesicle membrane; cytoplasmic vesicle; integral component of synaptic vesicle membrane;
Biological process	phosphate ion transport; synaptic transmission, glutamatergic; sodium-dependent phosphate transport; sodium ion transport; chloride transmembrane transport; ion transport; glutamate secretion; synaptic vesicle lumen acidification; brain development; long-term memory; excitatory postsynaptic potential; neurotransmitter transport; neural retina development; L-glutamate import; sequestering of neurotransmitter; sodium ion transmembrane transport; transmembrane transport; chemical synaptic transmission; neurotransmitter loading into synaptic vesicle; L-glutamate transmembrane transport; regulation of synaptic vesicle endocytosis; regulation of synapse structure or activity;
	Sources:Amigo / QuickGO
Orthologs
	57030
	72961
	ENSG00000104888
	ENSMUSG00000070570
	Q9P2U7
	Q3TXX4
	NM_020309
	NM_182993
	NP_064705
	NP_892038
	Wikidata
View/Edit Human	View/Edit Mouse

Vesicular glutamate transporter 1 (VGLUT1) is a protein that in humans is encoded by the SLC17A7 gene.^[5]^[6]^[7]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000104888 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000070570 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ni B, Du Y, Wu X, DeHoff BS, Rosteck PR Jr, Paul SM (Jul 1996). "Molecular cloning, expression, and chromosomal localization of a human brain-specific Na(+)-dependent inorganic phosphate cotransporter". J Neurochem. 66 (6): 2227–38. doi:10.1046/j.1471-4159.1996.66062227.x. PMID 8632143.
^ Aihara Y, Mashima H, Onda H, Hisano S, Kasuya H, Hori T, Yamada S, Tomura H, Yamada Y, Inoue I, Kojima I, Takeda J (Jun 2000). "Molecular cloning of a novel brain-type Na(+)-dependent inorganic phosphate cotransporter". J Neurochem. 74 (6): 2622–5. doi:10.1046/j.1471-4159.2000.0742622.x. PMID 10820226.
^ "Entrez Gene: SLC17A7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7".

Vesicular glutamate transporter 1

See also

References

Further reading