SLC22A9

SLC22A9
Identifiers
Aliases	SLC22A9, HOAT4, OAT4, OAT7, UST3H, ust3, solute carrier family 22 member 9
External IDs	OMIM: 607579; MGI: 3042283; HomoloGene: 137850; GeneCards: SLC22A9; OMA:SLC22A9 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	63,410,294 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	7,943,392 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; Brodmann area 9; ; gallbladder; ; prefrontal cortex; ; amygdala; ; islet of Langerhans; ; superior frontal gyrus; ; lymph node; ; putamen; ; hippocampal formation;
	Top expressed in
	proximal tubule; ; liver; ; metanephros; ; kidney;
	More reference expression data
	n/a
Gene ontology
Molecular function	sodium-independent organic anion transmembrane transporter activity; short-chain fatty acid transmembrane transporter activity; inorganic anion exchanger activity; urate transmembrane transporter activity;
Cellular component	integral component of membrane; plasma membrane; basolateral plasma membrane; integral component of plasma membrane; membrane;
Biological process	sodium-independent organic anion transport; hormone transport; short-chain fatty acid import; transmembrane transport; anion transmembrane transport; inorganic anion transport; urate transport; organic anion transport;
	Sources:Amigo / QuickGO
Orthologs
	114571
	171405
	ENSG00000149742
	ENSMUSG00000067656
	Q8IVM8
	Q76M72
	NM_080866
	NM_134256; NM_001361980
	NP_543142
	NP_599017; NP_001348909
	Wikidata
View/Edit Human	View/Edit Mouse

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Solute carrier family 22 member 9 is a protein that in humans is encoded by the SLC22A9 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000149742 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000067656 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Sun W, Wu RR, van Poelje PD, Erion MD (Apr 2001). "Isolation of a family of organic anion transporters from human liver and kidney". Biochem Biophys Res Commun. 283 (2): 417–22. doi:10.1006/bbrc.2001.4774. PMID 11327718.
^ Shin HJ, Anzai N, Enomoto A, He X, Kim do K, Endou H, Kanai Y (Apr 2007). "Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate". Hepatology. 45 (4): 1046–55. doi:10.1002/hep.21596. PMID 17393504. S2CID 42571618.
^ "Entrez Gene: SLC22A9 solute carrier family 22 (organic anion/cation transporter), member 9".

Zhou F, Hong M, You G (2007). "Regulation of human organic anion transporter 4 by progesterone and protein kinase C in human placental BeWo cells". Am. J. Physiol. Endocrinol. Metab. 293 (1): E57–61. doi:10.1152/ajpendo.00696.2006. PMID 17341544.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ekaratanawong S, Anzai N, Jutabha P, et al. (2005). "Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules". J. Pharmacol. Sci. 94 (3): 297–304. doi:10.1254/jphs.94.297. PMID 15037815.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ugele B, St-Pierre MV, Pihusch M, et al. (2003). "Characterization and identification of steroid sulfate transporters of human placenta". Am. J. Physiol. Endocrinol. Metab. 284 (2): E390–8. doi:10.1152/ajpendo.00257.2002. PMID 12409283. S2CID 348962.
Cha SH, Sekine T, Kusuhara H, et al. (2000). "Molecular cloning and characterization of multispecific organic anion transporter 4 expressed in the placenta". J. Biol. Chem. 275 (6): 4507–12. doi:10.1074/jbc.275.6.4507. PMID 10660625.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000149742 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000067656 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11327718-5] Sun W, Wu RR, van Poelje PD, Erion MD (Apr 2001). "Isolation of a family of organic anion transporters from human liver and kidney". Biochem Biophys Res Commun. 283 (2): 417–22. doi:10.1006/bbrc.2001.4774. PMID 11327718.

[pmid17393504-6] Shin HJ, Anzai N, Enomoto A, He X, Kim do K, Endou H, Kanai Y (Apr 2007). "Novel liver-specific organic anion transporter OAT7 that operates the exchange of sulfate conjugates for short chain fatty acid butyrate". Hepatology. 45 (4): 1046–55. doi:10.1002/hep.21596. PMID 17393504. S2CID 42571618.

[entrez-7] "Entrez Gene: SLC22A9 solute carrier family 22 (organic anion/cation transporter), member 9".

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SLC22A9

See also

References

Further reading