SLC2A12

SLC2A12
Identifiers
Aliases	SLC2A12, GLUT12, GLUT8, solute carrier family 2 member 12
External IDs	OMIM: 610372 MGI: 3052471 HomoloGene: 59263 GeneCards: SLC2A12
Gene location (Human)
Chr.	Chromosome 6 (human)
End	134,052,624 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	22,580,184 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; retinal pigment epithelium; ; duodenum; ; prostate; ; bronchial epithelial cell; ; body of stomach; ; biceps brachii; ; cardia; ; oral cavity; ; seminal vesicula;
	Top expressed in
	secondary oocyte; ; retinal pigment epithelium; ; stellate ganglion; ; Greater petrosal nerve; ; uterus; ; otolith organ; ; utricle; ; sternocleidomastoid muscle; ; cervix; ; submandibular gland;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	glucose transmembrane transporter activity; carbohydrate:proton symporter activity; transmembrane transporter activity; transporter activity; D-glucose transmembrane transporter activity;
Cellular component	cytoplasm; perinuclear region of cytoplasm; integral component of membrane; plasma membrane; membrane; endomembrane system; integral component of plasma membrane;
Biological process	carbohydrate transport; glucose import; transmembrane transport; hexose transmembrane transport; proton transmembrane transport; glucose transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	154091
	353169
	ENSG00000146411
	ENSMUSG00000037490
	Q8TD20
	Q8BFW9
	NM_145176
	NM_178934
	NP_660159
	NP_849265
	Wikidata
View/Edit Human	View/Edit Mouse

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Solute carrier family 2, facilitated glucose transporter member 12 is a protein that in humans is encoded by the SLC2A12 gene.^[5]^[6]^[7]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000146411 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000037490 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Joost HG, Thorens B (Jan 2002). "The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review)". Mol Membr Biol. 18 (4): 247–56. doi:10.1080/09687680110090456. PMID 11780753. S2CID 22667943.
^ Rogers S, Macheda ML, Docherty SE, Carty MD, Henderson MA, Soeller WC, Gibbs EM, James DE, Best JD (Feb 2002). "Identification of a novel glucose transporter-like protein-GLUT-12". Am J Physiol Endocrinol Metab. 282 (3): E733–8. doi:10.1152/ajpendo.2002.282.3.E733. PMID 11832379. S2CID 22919544.
^ "Entrez Gene: SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12".

Baumann MU, Deborde S, Illsley NP (2003). "Placental glucose transfer and fetal growth". Endocrine. 19 (1): 13–22. doi:10.1385/ENDO:19:1:13. PMID 12583599. S2CID 26301249.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Wood IS, Hunter L, Trayhurn P (2003). "Expression of Class III facilitative glucose transporter genes (GLUT-10 and GLUT-12) in mouse and human adipose tissues". Biochem. Biophys. Res. Commun. 308 (1): 43–9. doi:10.1016/S0006-291X(03)01322-6. PMID 12890477.
Rogers S, Chandler JD, Clarke AL, et al. (2003). "Glucose transporter GLUT12-functional characterization in Xenopus laevis oocytes". Biochem. Biophys. Res. Commun. 308 (3): 422–6. doi:10.1016/S0006-291X(03)01417-7. PMID 12914765.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Linden KC, DeHaan CL, Zhang Y, et al. (2006). "Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy". Am. J. Physiol. Renal Physiol. 290 (1): F205–13. doi:10.1152/ajprenal.00237.2004. PMID 16091581.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Stuart CA, Yin D, Howell ME, et al. (2006). "Hexose transporter mRNAs for GLUT4, GLUT5, and GLUT12 predominate in human muscle". Am. J. Physiol. Endocrinol. Metab. 291 (5): E1067–73. doi:10.1152/ajpendo.00250.2006. PMID 16803853. S2CID 41473791.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000146411 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000037490 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11780753-5] Joost HG, Thorens B (Jan 2002). "The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review)". Mol Membr Biol. 18 (4): 247–56. doi:10.1080/09687680110090456. PMID 11780753. S2CID 22667943.

[pmid11832379-6] Rogers S, Macheda ML, Docherty SE, Carty MD, Henderson MA, Soeller WC, Gibbs EM, James DE, Best JD (Feb 2002). "Identification of a novel glucose transporter-like protein-GLUT-12". Am J Physiol Endocrinol Metab. 282 (3): E733–8. doi:10.1152/ajpendo.2002.282.3.E733. PMID 11832379. S2CID 22919544.

[entrez-7] "Entrez Gene: SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12".

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SLC2A12

See also

References

Further reading