2-amino-2-methylpropionic acid

Structural formula
General
Surname	2-amino-2-methylpropionic acid
other names	2-amino-2-methylpropionic acid α-methylalanine 2-methylalanine α-aminoisobutyric acid
Molecular formula	C 4 H 9 NO 2
Brief description	White dust
External identifiers / databases
CAS number 62-57-7 EC number 200-544-0 ECHA InfoCard 100,000,495 PubChem 6119 ChemSpider 5891 DrugBank DB02952 Wikidata Q4596860
properties
Molar mass	103.2 g mol −1
Physical state	firmly
density	1.109 g cm −3
Melting point	> 300 ° C
solubility	soluble in water
safety instructions
GHS labeling of hazardous substances no GHS pictograms H and P phrases H: no H-phrases P: no P-phrases
Toxicological data	750 mg kg −1 ( LD 50 ,  mouse ,  ip )
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

2-Amino-2-methylpropionic acid is a chemical compound . It belongs to the non-proteinogenic amino acids . The α-carbon atom is also not a stereocenter; so it is not chiral.

Extraction

On a laboratory scale, 2-amino-2-methylpropionic acid can be obtained from acetone cyanohydrin and ammonium with subsequent hydrolysis.

Individual evidence

1. ↑ ^{a b c} data sheet α-aminoisobutyric acid from Sigma-Aldrich , accessed on April 23, 2013 ( PDF ).
2. ↑ Entry 2-amino isobutyric acid at Pharmasi Chemicals Co., accessed May 8, 2013.
3. ↑ ^{a b} Entry on 2-Amino-2-methylpropionic acid at ChemicalBook , accessed April 23, 2013.
4. ↑ Clarke, HT; Bean, H. J: α-Aminoisobutyric Acid In: Organic Syntheses . 11, 1931, p. 4, doi : 10.15227 / orgsyn.011.0004 ; Coll. Vol. 2, 1943, p. 29 ( PDF ).