2-methyl-2-pentanol

Structural formula
General
Surname	2-methyl-2-pentanol
other names	Dimethyl- n- propyl carbinol; Dimethylpropylcarbinol; 2-methylpentan-2-ol;
Molecular formula	C 6 H 14 O
Brief description	colorless liquid with an alcohol-like odor
External identifiers / databases
ECHA InfoCard	100.008.802
PubChem	11543
ChemSpider	11056
Wikidata	Q3278296
properties
Molar mass	102.18 g mol −1
Physical state	liquid
density	0.810 g cm −3
Melting point	-103 ° C
boiling point	120-122 ° C
solubility	soluble in water at 20 ° C (32 g / l at 20 ° C) and in ethanol
Refractive index	1.4100 (20 ° C)
safety instructions
H and P phrases	H: 226-319-335
	P: 210-261-303 + 361 + 353-305 + 351 + 338-405-501
Toxicological data	1410 mg kg −1 ( LD 50 , rat , oral )
	As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C

2-methyl-2-pentanol is a chemical compound from the group of alkanols .

Occurrence

The compound occurs as a metabolite found in the urine of rats exposed to methylpentane . It has also been partially detected in cooked rice.

Extraction and presentation

2-Methyl-2-pentanol can be obtained by reacting butyryl chloride with dimethyl zinc or acetone with propyl magnesium bromide .

properties

2-methyl-2-pentanol is a colorless liquid with an alcohol-like odor that is soluble in water and ethanol.

use

2-methyl-2-pentanol is used to study its antagonistic activity. It reacts with a second target site to change the spatial relationship between the hydrophobic agonist binding site and the allosteric site. It can initiate the polymerization of isocyanates and epoxides .

Individual evidence

↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k data sheet 2-methyl-2-pentanol, 99% from AlfaAesar, accessed on January 14, 2019 ( PDF )(JavaScript required) .
↑ ^a ^b ^c data sheet 2-methyl-2-pentanol, 99% from Sigma-Aldrich , accessed on January 14, 2019 ( PDF ).
^ Petros C. Mavroidis, N. David Palmeter: Regulated Chemicals Directory 1995 . Springer Science & Business Media, 2012, ISBN 978-94-011-4910-5 , pp. 594 ( limited preview in Google Book search).
↑ US Singh: Aromatic Rices . Int. Rice Res. Inst., 2000, ISBN 978-81-204-1420-4 , pp. 37 ( limited preview in Google Book search).
^ Frank C. Whitmore: Organic Chemistry, Volume One Part I: Aliphatic Compounds Part II: Alicyclic Compounds . Courier Corporation, 2012, ISBN 978-0-486-60700-9 , pp. 128 ( limited preview in Google Book search).

[Alfa-1] ↑ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k data sheet 2-methyl-2-pentanol, 99% from AlfaAesar, accessed on January 14, 2019 ( PDF )(JavaScript required) .

[Sigma-2] ta sheet 2-methyl-2-pentanol, 99% from Sigma-Aldrich , accessed on January 14, 2019 ( PDF ).

[Petros_C._Mavroidis,_N._David_Palmeter-3] Petros C. Mavroidis, N. David Palmeter: Regulated Chemicals Directory 1995 . Springer Science & Business Media, 2012, ISBN 978-94-011-4910-5 , pp. 594 ( limited preview in Google Book search).

[U._S._Singh-4] US Singh: Aromatic Rices . Int. Rice Res. Inst., 2000, ISBN 978-81-204-1420-4 , pp. 37 ( limited preview in Google Book search).

[Frank_C._Whitmore-5] Frank C. Whitmore: Organic Chemistry, Volume One Part I: Aliphatic Compounds Part II: Alicyclic Compounds . Courier Corporation, 2012, ISBN 978-0-486-60700-9 , pp. 128 ( limited preview in Google Book search).