3-amino-9-ethylcarbazole

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Structural formula
3-amino-9-ethylcarbazole
General
Surname 3-amino-9-ethylcarbazole
other names
  • 9-ethylcarbazol-3-amine
  • 9-ethyl-9 H -carbazol-3-amine
  • AEC
Molecular formula C 14 H 14 N 2
External identifiers / databases
CAS number 132-32-1
EC number 205-057-7
ECHA InfoCard 100.004.599
PubChem 8588
Wikidata Q21099619
properties
Molar mass 210.27 g mol −1
Physical state

firmly

Melting point

127 ° C

safety instructions
GHS hazard labeling from  Regulation (EC) No. 1272/2008 (CLP) , expanded if necessary
08 - Dangerous to health 06 - Toxic or very toxic

danger

H and P phrases H: 301-350
P: 201-301 + 310-308 + 313
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

3-Amino-9-ethylcarbazole (AEC) is a chemical compound from the group of carbazoles .

properties

3-Amino-9-ethylcarbazole is used in biochemistry as a chromogenic substrate for immunostaining with a horseradish peroxidase and, after oxidation with hydrogen peroxide, produces a red dye which is insoluble in water but soluble in ethanol , e.g. B. in an immunoperoxidase assay , western blot and immunohistochemistry .

Individual evidence

  1. ↑ a b c Entry on 3-Amino-9-ethylcarbazole in the GESTIS substance database of the IFA , accessed on February 1, 2016(JavaScript required) .
  2. ↑ Entry on 9-ethylcarbazol-3-ylamine in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on August 1, 2016. Manufacturers or distributors can expand the harmonized classification and labeling .
  3. ^ G. Glass, JA Papin, JW Mandell: SIMPLE: a sequential immunoperoxidase labeling and erasing method. In: The journal of histochemistry and cytochemistry: official journal of the Histochemistry Society. Volume 57, number 10, October 2009, pp. 899-905, doi : 10.1369 / jhc.2009.953612 , PMID 19365090 , PMC 2746723 (free full text).
  4. ^ AE Novak, AB Ribera: Immunocytochemistry as a tool for zebrafish developmental neurobiology. In: Methods in cell science: an official journal of the Society for In Vitro Biology. Volume 25, number 1-2, 2003, pp. 79-83, doi : 10.1023 / B: MICS.0000006894.43940.b1 , PMID 14739591 .