Benzyl 4-hydroxybenzoate
Structural formula | ||||||||||||||||||||||
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General | ||||||||||||||||||||||
Surname | Benzyl 4-hydroxybenzoate | |||||||||||||||||||||
other names |
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Molecular formula | C 14 H 12 O 3 | |||||||||||||||||||||
Brief description |
white odorless solid |
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properties | ||||||||||||||||||||||
Molar mass | 228.25 g mol −1 | |||||||||||||||||||||
Physical state |
firmly |
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Melting point |
110-114 ° C |
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solubility |
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safety instructions | ||||||||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
4-Hydroxybenzoic acid benzyl ester is a chemical compound from the group of parabens .
Extraction and presentation
The compound can be prepared by esterification of p- hydroxybenzoic acid with benzyl alcohol or by reaction of benzyl chloride with the sodium salt of p- hydroxybenzoic acid.
properties
Benzyl 4-hydroxybenzoate is a white, odorless solid that is soluble in ethanol. The compound can form salts with strong alkalis and is subject to hydrolysis by both acids and alkalis.
use
Benzyl 4-hydroxybenzoate has been used as a preservative for cosmetics since 1943 . It is more effective against fungi and gram-positive bacteria than against gram-negative bacteria. In the EU, the compound may no longer be used in cosmetics.
Individual evidence
- ↑ a b c d e f Data sheet Benzyl 4-hydroxybenzoate, 99% from AlfaAesar, accessed on December 14, 2019 ( PDF )(JavaScript required) .
- ↑ a b c F.v. Bruchhausen, S. Ebel, AW Frahm, E. Hackenthal: Hager's handbook of pharmaceutical practice substances AD . Springer-Verlag, 2013, ISBN 978-3-642-57995-0 , pp. 441 ( limited preview in Google Book search).
- ↑ a b c Data sheet Benzyl 4-hydroxybenzoate, 99% from Sigma-Aldrich , accessed on December 14, 2019 ( PDF ).
- ↑ a b c d Final Report on the Safety Assessment of Benzylparaben , In: Journal of the American College of Toxicology , Volume 5, Number 5, 1986. doi : 10.3109 / 10915818609141913 (currently unavailable) .
- ↑ Parabens in cosmetics: EU tightened the rules for parabens in 2015: Parabens in cosmetics: EU tightened the rules for parabens in 2015 , accessed on December 14, 2019.