4-iodosalicylic acid

Structural formula
General
Surname	4-iodosalicylic acid
other names	4-iodo-2-hydroxybenzoic acid
Molecular formula	C 7 H 5 IO 3
Brief description	colorless needles that turn brown at 200 ° C
External identifiers / databases
CAS number 16870-28-3 EC number 605-527-5 ECHA InfoCard 100.124.594 PubChem 72874 ChemSpider 65706 Wikidata Q229989
properties
Molar mass	264.02 g · mol -1
Physical state	firmly
Melting point	228-230  ° C (dec.)
safety instructions
GHS labeling of hazardous substances danger H and P phrases H: 301-318 P: 280-301 + 310-305 + 351 + 338
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

4-Iodosalicylic acid is a chemical compound that belongs to both phenolic acids and halogen aromatic compounds and is formally derived from salicylic acid. They are colorless needles that turn brown at 200 ° C.

presentation

The synthesis of 4-iodosalicylic acid starts from the acetylation of 4-nitro- o -toluidine.

Reactions

4-Iodosalicylic acid forms a red-violet color with iron (III) chloride . Esterification with methanol results in the methyl ester (CAS number: 18179-39-0) with a melting range of 69 to 73 ° C. The ethyl ester has a melting point of 112 ° C. Another derivative is 4-iodoacetylsalicylic acid, which can be prepared by acetylation (melting point 156 ° C.).

Individual evidence

1. ^ ^{A b c d} T. E. Thorpe: A Dictionary of Applied Chemistry , Volume 6. Longmans, Green and Co. 1926, p. 24.
2. ^ ^{A b} Hugh Mills Bunbury: Dictionary of organic compounds: the constitution and physical and chemical properties of the principal carbon compounds and their derivatives, together with the relevant literature references ". Volume 3 of Dictionary of Organic Compounds, Oxford university press, 1953. P. 44.
3. ↑ ^{a b c} data sheet 2-Hydroxy-4-iodobenzoic acid from Sigma-Aldrich , accessed on March 18, 2011 ( PDF ).
4. ↑ ^{a b} entry at orgch.ru .