Alexander Knuth

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Alexander Knuth (born May 3, 1948 in Wolfen) is a German oncologist . He is known for his work on tumor immunology .

Life

Knuth studied medicine at the Free University of Berlin . After the state examination in 1973, he received his doctorate in pathology from the University of Zurich in 1974 . At the Moabit Hospital he was trained as a specialist in hematology and internal oncology . When Lloyd J. Old , and Herbert F. Oettgen he worked from 1978 to 1980 as a research assistant at the Memorial Sloan-Kettering Cancer Center (MSKCC) in New York . There he also passed the American state examination. From 1981 Knuth was a research assistant and senior physician at the University Hospital in Mainz , where he completed his habilitation in 1987 with the thesis The extrahepatic bile duct carcinoma in tissue culture as a model for the development of a new tumor marker system . In 1991 he received a visiting professorship at the Fred Hutchinson Cancer Research Center in Seattle . Knuth was chief physician of hematology / oncology at the Nordwest-Krankenhaus in Frankfurt am Main and director of the center for clinical studies there at the Ludwig Institute for Cancer Research , before becoming professor of internal medicine ( oncology ) at the University of Zurich and head of oncology at the university hospital in 2003 Zurich became. He has been medical director of the National Center for Cancer Care & Research (NCCCR) in Doha , the capital of Qatar , since 2013 .

Act

Knuth was part of the group that identified and cloned the first tumor antigen (known today as part of MAGEA1 , melanoma antigen family A, 1 ).

Knuth specializes in the treatment of malignant tumors of the gastrointestinal tract as well as tumor immunology and cancer immunotherapy . He works on clinically oriented research and development programs to develop new immune-based approaches such as active or passive immunization.

Knuth has published more than 150 scientific publications , including over 20 systematic reviews on the subject of immunotherapies against cancer.

Awards (selection)

Web links

Individual evidence

  1. ↑ DNB 891643141
  2. ↑ team at hs-lifesciences; accessed on March 15, 2014
  3. ↑ P. van der Bruggen, C. Traversari, P. Chomez, C. Lurquin, E. De Plaen, B. Van den Eynde, A. Knuth, T. Boon: A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. In: Science. Volume 254, Number 5038, December 1991, pp. 1643-1647, ISSN  0036-8075 . PMID 1840703 .
  4. ↑ Invitation to the presentation of the Johann Georg Zimmermann Prize 2013/2014 (PDF, 69 kB)
personal data
SURNAME Knuth, Alexander
BRIEF DESCRIPTION German oncologist
DATE OF BIRTH May 3, 1948
PLACE OF BIRTH Wolfen