Alfons Maria Jakob

from Wikipedia, the free encyclopedia
Alfons Maria Jakob. around 1915

Alfons Maria Jakob (born July 2, 1884 in Aschaffenburg ; † October 17, 1931 in Hamburg ) was a German neurologist and psychiatrist with important contributions in the field of neuropathology (for example on diseases such as multiple sclerosis, neurosyphilis and Friedreich's ataxia). He is one of the two namesake for Creutzfeldt-Jakob disease , an incurable brain disease .

Life

Alfons Jakob, son of a shopkeeper, studied medicine in Munich , Berlin and Strasbourg . The member of the Strasbourg Catholic German Student Union Badenia was a co-founder of the Catholic Student Union KDSt.V. in 1905. Rappoltstein (Strasbourg) Cologne in the CV . He was in 1908 with the work at the former Kaiser-Wilhelm University in Strasbourg The pathogenesis of pseudobulbar (apparent paralysis of the medulla oblongata) PhD . After obtaining his medical license in 1909, he began his clinical work with the psychiatrist Emil Kraepelin and worked in the departments of neuromorphology under Alois Alzheimer and Franz Nissl in Munich.

In 1911 Jakob became head of the pathology laboratory at the Friedrichsberg State Hospital , and from 1914 director of the anatomical department. After his assignment in the First World War as head of the neurological-psychiatric department of the war hospital I in Brussels and doctor at the Malone nerve convalescent home. After the end of the First World War, he set up his own practice for neurology in 1919. In 1919 he completed his habilitation in neurology and psychiatry at the University of Hamburg . There he was appointed professor of neurology in 1924 .

Alfons Jakob researched the consequences of injuries to peripheral nerves and secondary nerve degeneration, the morphological changes in multiple sclerosis , Friedreich's ataxia , glionural juvenile dystrophy ( Alpers disease ).

Shortly after the Kiel neurologist Hans Gerhard Creutzfeldt , he described the so-called Creutzfeldt-Jakob disease for the first time independently of him . He noticed "present dementia" in three patients and reported on his clinical and brain pathological examinations in 1920 at the German Neurological Congress in Leipzig. In the following detailed written descriptions he spoke of a "spongiform encephalopathy" in humans and suspected a transferability.

Jakob published five monographs and more than 150 articles in professional journals. He was a valued teacher and his laboratory attracted scientists from Japan , Russia , Italy, and the United States .

After contracting osteomyelitis of the thigh in 1924 with subsequent abscess formation , he died in 1931 at the age of 47 as a result of paralytic ileus .

Fonts (selection)

Jakob wrote around 150 specialist articles and five monographs, including:

  • The extrapyramidal diseases with special consideration of the pathological anatomy and histology and the pathopsychology of movement disorders. In: Monographs from the entire field of neurology and psychiatry. Volume 37, Berlin 1923.
  • Normal and pathological anatomy and histology of the cerebrum. Reprint from Handbuch der Psychiatrie. Leipzig / Vienna 1927–1928.
  • The cerebellum. In: Handbook of microscopic anatomy. Berlin 1928.
  • The syphilis of the brain and its skins. In: Oswald Bumke (Hrsg.): Handbuch der Geisteskrankheiten. Berlin 1930.

Web links

Individual evidence

  1. ↑ Sabine Schuchert: Creutzfeldt and Jakob were both on the trail of a riddle Deutsches Ärzteblatt 2019, Volume 116, Issue 49 of December 6, 2019, page (60), link accessed on December 15, 2019, 9:18 p.m. CEST
personal data
SURNAME Jakob, Alfons Maria
BRIEF DESCRIPTION German neurologist
DATE OF BIRTH July 2, 1884
PLACE OF BIRTH Aschaffenburg
DATE OF DEATH October 17, 1931
Place of death Hamburg