Attila Becskei

Attila Becskei, 2012

Attila Becskei (born December 14, 1973 in Bačka Topola ) is a Hungarian systems biologist and professor at the Biozentrum of the University of Basel , Switzerland .

Life

Attila Becskei finished his studies in medicine in 1998 at the University of Szeged , Hungary, and also studied physical chemistry . After completing his PhD at the European Molecular Biology Laboratory (EMBL) in Heidelberg , Attila Becskei carried out research at the Massachusetts Institute of Technology (MIT) in Cambridge , USA until 2005 . From 2006 he did research as an assistant professor at the University of Zurich . In 2011, Attila Becskei was appointed professor at the Biozentrum of the University of Basel , where he continues to conduct research and teach synthetic microbiology and systems biology.

Act

Becskei uses experimental genetic engineering methods and mathematical models to research how genes that control cell differentiation are interconnected. The focus of his research is on feedback mechanisms and stochastic and epigenetic control of gene expression in yeast and mammalian cells. He was able to show that the persistence of epigenetic memory is determined by the distance between the binding sites of the epigenetic regulators along the chromosome .

Publications (selection)

Complete list of publications

• A. Becskei, L. Serrano: Engineering stability in gene networks by autoregulation. In: Nature . 405 (6786), 2000, pp. 590-593. PMID 10850721
• M. Acar, A. Becskei, A. van Oudenaarden: Enhancement of cellular memory by reducing stochastic transitions. In: Nature. 435 (7039), 2005, pp. 228-232. PMID 15889097
• J. Kelemen, P. Ratna, S. Scherrer, A. Becskei: Spatial epigenetic control of mono- and bistable gene expression. In: PLOS Biology . 8 (3), 2010, p. E1000332. PMID 20305717
• C. Hsu, S. Scherrer, A. Buetti Dinh, P. Ratna, J. Pizzolato, V. Jaquet, Becskei A: Stochastic signaling rewires the interaction map of a multiple feedback network during yeast evolution. In: Nature Communications. 3, 2012, p. 682. PMID 22353713

Web link

• Research group Attila Becskei at the Biozentrum of the University of Basel , accessed on January 27, 2015.

Individual evidence

1. ↑ UZH Institute of Molecular Life Sciences
2. ↑ Curriculum Vitae biozentrum.unibas.ch, accessed on January 27, 2015
3. ↑ Engineering stability in gene networks by autoregulation nature.com, accessed January 27, 2015.
4. ↑ Stochastic signaling rewires the interaction map of a multiple feedback network during yeast evolution nature.com, accessed on January 27, 2015.
5. ↑ János Z. Kelemen, Prasuna Ratna, Simone Scherrer, Attila Becskei, Andre Levchenko: Spatial Epigenetic Control of Mono- and Bistable Gene Expression. In: PLoS Biology. 8, 2010, p. E1000332, doi : 10.1371 / journal.pbio.1000332 . PMC 2838748 (free full text)
6. ↑ Complete list of publications at Biozentrum.unibas.ch, accessed on January 27, 2015.