Cefpodoxime proxetil

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Structural formula
Structural formula of cefpodoxime proxetil
General
Surname Cefpodoxime proxetil (Cefpodoxime proxetil)
other names

1-propan-2-yloxycarbonyloxyethyl- (6 R , 7 R ) -7 - {[(2 Z ) -2- (2-amino-1,3-thiazol-4-yl) -2-methoxyiminoacetyl] amino} - 3- (methoxymethyl) -8-oxo-5-thia-1-azabicyclo [4.2.0] oct-2-ene-2-carboxylate

Molecular formula C 21 H 27 N 5 O 9 S 2
External identifiers / databases
CAS number 87239-81-4
EC number 918-886-0
ECHA InfoCard 100.128.191
PubChem 6526396
ChemSpider 5014485
DrugBank DB01416
Wikidata Q1052672
Drug information
ATC code

J01 DD13

Drug class

β-lactam antibiotics
(3rd generation cephalosporin as an oral prodrug)

properties
Molar mass 557.60 g · mol -1
safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS labeling of hazardous substances
08 - Dangerous to health

danger

H and P phrases H: 317-334
P: ?
Toxicological data
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Cefpodoxime proxetil is a prodrug of the antibiotic cefpodoxime , a modification with an absorption ester to enable its absorption after oral administration. During the passage through the intestinal mucosa , the pharmacologically active parent substance is restored by hydrolysis by means of non-specific esterases .

Individual evidence

  1. ↑ Template: CL Inventory / not harmonized There is not yet a harmonized classification for this substance . A labeling of 1-propan-2-yloxycarbonyloxyethyl (6R, 7R) -7 - [[(2Z) -2- (2-amino-1, 3-thiazol-4-yl) - is shown, which is derived from a self-classification by the distributor 2-methoxyiminoacetyl] amino] -3- (methoxymethyl) -8-oxo-5-thia-1-azabicyclo [4.2.0] oct-2-ene-2-carboxylate in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on December 21, 2018.
  2. ↑ a b Entry on cefpodoxime proxetil in the ChemIDplus database of the United States National Library of Medicine (NLM), accessed on December 21, 2018.

Web links