Cefpodoxime proxetil
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General | ||||||||||||||||||||||
Surname | Cefpodoxime proxetil (Cefpodoxime proxetil) | |||||||||||||||||||||
other names |
1-propan-2-yloxycarbonyloxyethyl- (6 R , 7 R ) -7 - {[(2 Z ) -2- (2-amino-1,3-thiazol-4-yl) -2-methoxyiminoacetyl] amino} - 3- (methoxymethyl) -8-oxo-5-thia-1-azabicyclo [4.2.0] oct-2-ene-2-carboxylate |
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Molecular formula | C 21 H 27 N 5 O 9 S 2 | |||||||||||||||||||||
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Drug information | ||||||||||||||||||||||
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Drug class |
β-lactam antibiotics |
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properties | ||||||||||||||||||||||
Molar mass | 557.60 g · mol -1 | |||||||||||||||||||||
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Toxicological data | ||||||||||||||||||||||
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Cefpodoxime proxetil is a prodrug of the antibiotic cefpodoxime , a modification with an absorption ester to enable its absorption after oral administration. During the passage through the intestinal mucosa , the pharmacologically active parent substance is restored by hydrolysis by means of non-specific esterases .
Individual evidence
- ↑ harmonized classification for this substance . A labeling of 1-propan-2-yloxycarbonyloxyethyl (6R, 7R) -7 - [[(2Z) -2- (2-amino-1, 3-thiazol-4-yl) - is shown, which is derived from a self-classification by the distributor 2-methoxyiminoacetyl] amino] -3- (methoxymethyl) -8-oxo-5-thia-1-azabicyclo [4.2.0] oct-2-ene-2-carboxylate in the Classification and Labeling Inventory of the European Chemicals Agency (ECHA), accessed on December 21, 2018. There is not yet a
- ↑ a b Entry on cefpodoxime proxetil in the ChemIDplus database of the United States National Library of Medicine (NLM), accessed on December 21, 2018.
Web links
- Cefpodoxim-Proxetil - a new cephalosporin for oral use in the magazine for chemotherapy, issue 1, Berlin 1992