Charles Lee (geneticist)
Charles Lee (* 1969 in Seoul ) is a Canadian geneticist of Korean descent at Harvard Medical School and the Jackson Laboratory .
Life
Lee was born in Korea but grew up in Canada from the age of one . He earned a Ph.D. from the University of Alberta in 1996. in Medical Sciences ( Medicine ). He worked as a postdoctoral fellow at Cambridge University in England before completing his residency in cytogenetics at Harvard Medical School from 1998 . In 2003 he received his first professorship (assistant professor) for pathology at Harvard Medical School, and in 2008 he became an associate professor. Since 2006 he has headed the cytogenetics department at Harvard Medical School and is an associate member of the Broad Institute of the Massachusetts Institute of Technology (MIT) and Harvard University.
Lee has also headed the cytogenetics department at Jackson Laboratory in Bar Harbor , Maine , since 2013 . He is also an honorary professor at the Chinese University of Hong Kong and directs molecular genetics at Brigham and Women's Hospital , a teaching hospital at Harvard Medical School.
Act
In 2004, Lee discovered, using DNA chip technology , that in addition to single nucleotide polymorphisms (differences in individual base pairs of DNA ) there was also a wide range of variations in the number of gene copies ( Gene copy number variants , CNV) as variants in the human genome gives. Lee founded an international consortium of scientists who presented a genetic map of the human genome based on the CNV in 2006. In 2007 Lee was able to show that environmental conditions and human behavior have an influence on the CNV regions. CNV serve as the basis for genetic testing and as an approach to individualizing cancer therapy (see personalized medicine ).
As part of the 1000 Genome Project at Jackson Laboratory, Lee is investigating structural variations in human genomes, genetic aberrations and their relationships to congenital malformations , the evolution of genomes in (non-human) primates and their influence on genome stability and the genetics of Cancer and tries to identify appropriate biomarkers .
Since 2014, Thomson Reuters Lee has been one of the favorites for a Nobel Prize ( Thomson Reuters Citation Laureates ) due to the number of his citations .
Awards (selection)
- 2008 Ho Am Prize for Medicine
- 2012 Fellow of the American Association for the Advancement of Science
Web links
- Charles Lee and Lee Lab at Jackson Laboratory (jax.org)
Individual evidence
- ↑ BWH Cytogeneticist to Receive Korean “Nobel Prize” ( Memento from October 20, 2014 in the Internet Archive )
- ↑ 2014 Predictions - Medicine at Thomson Reuters (sciencewatch.com); accessed on September 27, 2014.
- ↑ Ho-Am Prize 2008 Laureates - Medicine at the Ho-Am Foundation (hoamprize.samsungfoundation.org); accessed on September 27, 2014.
| personal data | |
|---|---|
| SURNAME | Lee, Charles |
| BRIEF DESCRIPTION | Canadian geneticist |
| DATE OF BIRTH | 1969 |
| PLACE OF BIRTH | Seoul |