Deoxyadenosine triphosphate

Structural formula
General
Surname	Deoxyadenosine triphosphate
other names	2'-deoxyadenosine-5'-triphosphate
Molecular formula	C 10 H 16 N 5 O 12 P 3
External identifiers / databases
CAS number 1927-31-7 74299-50-6 (disodium salt) EC number 217-662-3 ECHA InfoCard 100.016.058 PubChem 15993 ChemSpider 15194 DrugBank DB03222 Wikidata Q201090
properties
Molar mass	491.18 g mol −1
safety instructions
GHS labeling of hazardous substances Disodium salt no GHS pictograms H and P phrases H: no H-phrases P: no P-phrases
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Deoxyadenosine triphosphate ( dATP ) is one of four synthetic building blocks of nucleic acid DNA . It consists of deoxyribose , the base adenine and a triphosphate group.

biosynthesis

The deoxyribonucleoside triphosphates are synthesized in the cell as high-energy compounds from 2'-deoxyribonucleotide-5'-monophosphate through two successive phosphorylation steps with ATP as a phosphate group donor.

function

dATP is an energy-rich precursor for deoxyadenosine monophosphate , one of four building blocks of DNA , which is a sequence of nucleoside monophosphates . The genetic code of DNA results from the sequence of the bases of these building blocks. Since the base of dATP is adenine, this building block encodes the A of this code.

literature

• Peter Karlson: Short textbook of biochemistry . 12th edition, Thieme, Stuttgart, New York 1984, ISBN 3-13-357812-X .

Individual evidence

1. ↑ ^{a b} Data sheet 2′-Deoxyadenosine 5′-triphosphate disodium salt, ≥97% from Sigma-Aldrich , accessed on December 21, 2019 ( PDF ).