Daniel J. Klionsky

Daniel Jay Klionsky (* 1958 in California ) is an American biochemist and molecular biologist .

Life

Klionsky earned a bachelor's degree in biology from the University of California, Los Angeles in 1980 and a PhD from Stanford University in 1986 . His dissertation is entitled Assembly of the Proton-translocating ATPase of Escherichia Coli . He worked as a postdoctoral fellow at the California Institute of Technology (Caltech). In 1990 he received a position as Assistant Professor of Microbiology at the University of California, Davis , and in 1997 he was given a full professorship there. In 1997/1998 he had a research year as a Guggenheim Fellow at Dartmouth Medical School . Klionsky has been at the University of Michigan at Ann Arbor since 2000 , initially in the Department of Molecular, Cellular and Developmental Biology and in the Department of Biochemistry in the Medical School there . In 2003 he moved to the Life Sciences Institute there , and has been Alexander G. Ruthven Professor of Life Sciences since 2006 .

Act

Klionsky is concerned with autophagocytosis , a process used by eukaryotic cells to break down organelles , particularly their subtypes of mitophagy , where mitochondria are broken down, pexophagy , where peroxisomes are broken down, and reticulophagy , where the endoplasmic reticulum is broken down. He uses baker's yeast ( Saccharomyces cerevisiae ) as a model organism .

Klionsky is the editor of the scientific journal Autophagy .

Since 2013 Thomson Reuters has counted him among the favorites for a Nobel Prize ( Thomson Reuters Citation Laureates ) due to the number of his citations .

Fonts (selection)

• Autophagy. Landes Bioscience 2003 ISBN 978-1-58706-203-2
• Methods in Enzymology. Volume 451
  • Part A: Autophagy: Lower Eukaryotes and Non Mammalian Systems. Academic Press 2008 ISBN 978-0-12-374548-4
  • Part B: Autophagy in Mammalian Systems. Academic Press 2009 ISBN 978-0-12-374547-7
  • Part C: Autophagy in Disease and Clinical Applications. Academic Press 2009 ISBN 978-0-12-374936-9

Awards (selection)

• 2008 Fellow of the American Association for the Advancement of Science
• 2015 Van Deenen Medal
• 2019 member of the American Academy of Arts and Sciences

Web links

• Klionsky Lab at the University of Michigan (umich.edu)
• Klionsky Lab at the Life Sciences Institute of the University of Michigan (umich.edu)
• Daniel Klionsky at f1000.com
• Daniel Klionsky at sciencewatch.com
• Interview (2013) with Daniel Klionsky at sciencewatch.com

Individual evidence

1. ^ John Simon Guggenheim Foundation - Daniel J. Klionsky. In: gf.org. Retrieved February 13, 2016 . 
2. ↑ 2013 Predictions at Thomson Reuters (sciencewatch.com); Retrieved September 27, 2013
3. ^ Daniel Klionsky wins van Deenen Medal. October 30, 2015, accessed March 11, 2019 .