Daniel W. Bradley

from Wikipedia, the free encyclopedia

Daniel W. Bradley (born July 13, 1941 in Palo Alto , California ) is an American virologist , known for research on hepatitis viruses.

Bradley graduated from San Jose State College (bachelor's degree in 1964) and received his PhD from the University of Arizona at Tucson in 1970. From 1971 he worked at the Centers for Disease Control , first in Phoenix (Arizona) and later in Atlanta , where he headed the hepatitis department. He was with the CDC until 1994.

In the early 1980s, he isolated a purified form of the hepatitis C virus (at that time still hepatitis Non A Non B) in chimpanzee serum. This led (from 1982) to a collaboration with the company Chiron Corporation (where Michael Houghton was among others ), where a hepatitis C test was developed, which from the beginning of the 1990s on the identification of hepatitis C-positive samples Blood transfusions made possible. The hepatitis C virus causes chronic liver cirrhosis and liver cancer .

In the 1990s, Bradley and Chiron started litigation over patent and compensation issues.

In 1988 he also succeeded in molecularly characterizing the hepatitis E virus.

In 1993 he received the Robert Koch Prize with Houghton (and Hans-Georg Rsameee ) and in 1992 the Karl Landsteiner Memorial Award from the AABB, and in 2013 the Canada Gairdner International Award .

Web links

Individual evidence

  1. JL Boyer et al. a. (Ed.) Liver cirrhosis and its development , Kluwer 2001, p. 344
  2. Judgment in the Bradley v. Chiron case
  3. A team there with Houghton, Qui-Lim Choo and George C. Kuo was able to clone parts of the virus in the late 1980s and genetically characterize it, which was then renamed Hepatitis C. That made the test possible to develop
  4. Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome , Science, Volume 244, 1989, pp. 359-362.