De-Bao Wang

De-Bao Wang , also TP Wang, ( Chinese  王德 寶  /  王德 宝 , Pinyin Wáng Débǎo , W.-G. Wang Te-pao; born  May 7, 1918 in Huangqiao , Taixing in Jiangsu Province ; † 2002 ) was a Chinese biochemist , known for research on transfer RNA .

Wang graduated from Chongqing University with a bachelor's degree in 1940, where he was an assistant and lecturer. In 1947 he went to Louisiana State University in Baton Rouge and in 1948 to Washington University , where he received his master's degree in 1949. In 1951 he received his PhD from Case Western Reserve University . He was a post-doctoral student at Johns Hopkins University before returning to China in 1955. There he was at the Institute of Biochemistry of the Chinese Academy of Sciences in Shanghai , where he became a professor in 1960.

From 1962 to 1982 he worked with around 100 employees on the total synthesis of alanine t-RNA (it was the first t-RNA to be sequenced in 1964 by Nobel Prize winner Robert W. Holley ). This was the first biologically active t-RNA to be synthesized in total synthesis.

literature

• Wang et al. a., Total synthesis of yeast alanine transfer ribonucleic acid, Sci. Sin. B, Vol. 26, 1983, pp. 464-481
• Pötsch: Article De Bao Wang (Te Pao), in: Winfried R. Pötsch (lead), Annelore Fischer, Wolfgang Müller: Lexicon important chemists , Harri Deutsch 1989, p. 444

Web links

• You-Shang Zhang: The development of biochemistry and molecular biology in China, IUBMB Life, Volume 61, 2009, pp. 549-554, pdf