Deoxycytidine triphosphate

Structural formula
General
Surname	Deoxycytidine triphosphate
other names	2'-deoxycytidine-5'-triphosphate
Molecular formula	C 9 H 16 N 3 O 13 P 3
External identifiers / databases
CAS number 2056-98-6 102783-51-7 (di-sodium salt) EC number 218-153-9 ECHA InfoCard 100.016.504 PubChem 65091 ChemSpider 58601 DrugBank DB03258 Wikidata Q424680
properties
Molar mass	467.16 g mol −1
safety instructions
GHS labeling of hazardous substances no GHS pictograms H and P phrases H: no H-phrases P: no P-phrases
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Deoxycytidine triphosphate (dCTP) is one of four building blocks of nucleic acid DNA . It consists of a deoxyribose , the base cytosine and a triphosphate group.

biosynthesis

The deoxyribonucleoside triphosphates are synthesized in the cell as high-energy compounds from 2'-deoxyribonucleotide-5'-monophosphate, through two successive phosphorylation steps with ATP as a phosphate group donor.

function

dCTP is one of the four building blocks of DNA . When it attaches to the DNA strand, pyrophosphate is split off. The genetic code of DNA results from the sequence of the bases of these building blocks. Since the base of dCTP is cytosine , this building block encodes the C of this code.

See also

• CTP , a related substance. The two triphosphates differ only in the hydroxyl group at the 2'-C of the deoxyribose , which dCTP is missing. While dCTP is a building block of DNA , CTP is a building block of RNA .
• DNA: Building Blocks An overview of the role of deoxyribonucleotides in the structure of DNA .
• dATP , dGTP , dTTP are the three other building blocks of DNA.

Individual evidence

1. ↑ ^{a b} Data sheet 2′-Deoxyadenosine 5′-triphosphate disodium salt, ≥97% from Sigma-Aldrich , accessed on February 13, 2013 ( PDF ).

literature

• Peter Karlson: Short textbook of biochemistry . 12th edition, Thieme, Stuttgart, New York 1984, ISBN 3-13-357812-X .