Deoxyguanosine triphosphate
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| Surname | Deoxyguanosine triphosphate | |||||||||||||||||||||
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2'-deoxyguanosine-5'-triphosphate |
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| Molecular formula | C 10 H 16 N 5 O 13 P 3 | |||||||||||||||||||||
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| Molar mass | 507.18 g mol −1 | |||||||||||||||||||||
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| As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . | ||||||||||||||||||||||
Deoxyguanosine triphosphate (dGTP) is one of four building blocks of nucleic acid DNA . It consists of a deoxyribose , the base guanine and a triphosphate group.
biosynthesis
The deoxyribonucleoside triphosphates are synthesized in the cell as high-energy compounds from 2'-deoxyribonucleotide-5'-monophosphate, through two successive phosphorylation steps with ATP as a phosphate group donor.
function
dGTP is one of four building blocks of DNA . The genetic code of DNA results from the sequence of the bases of these building blocks. Since the base of dGTP is guanosine , this building block encodes the G of this code.
See also
- GTP , a related substance. The only difference between the two triphosphates is the hydroxyl group at the 2'-C of deoxyribose , which dGTP lacks.
- DNA: Building Blocks An overview of the role of deoxyribonucleotides in the structure of DNA .
- dATP , dCTP , dTTP are the three other building blocks of DNA.
literature
- Jeremy M. Berg, John L. Tymoczko, Lubert Stryer : Biochemistry. 6 edition, Spektrum Akademischer Verlag, Heidelberg 2007. ISBN 978-3-8274-1800-5 .
- Donald Voet, Judith G. Voet: Biochemistry. 3rd edition, John Wiley & Sons, New York 2004. ISBN 0-471-19350-X .
- Bruce Alberts , Alexander Johnson, Peter Walter, Julian Lewis, Martin Raff, Keith Roberts: Molecular Biology of the Cell , 5th Edition, Taylor & Francis 2007, ISBN 978-0-81534106-2 .
Individual evidence
- ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
literature
- Peter Karlson: Short textbook of biochemistry . 12th edition, Thieme, Stuttgart, New York 1984. ISBN 3-13-357812-X