Dirk Bumann

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Dirk Bumann, 2011

Dirk Bumann (* 1967 in Berlin ) is a German infection biologist and professor at the Biozentrum of the University of Basel , Switzerland .

Life

Dirk Bumann studied chemistry and biology at the Free University of Berlin . In 1994 he did his doctorate at the Max Planck Institute for Biochemistry in Martinsried and then did research as a postdoc at the Marine Biological Laboratory , Woods Hole, USA. From 1997 to 2004 Dirk Bumann was a research group leader at the Max Planck Institute for Infection Biology in Berlin, from 2004 to 2007 he researched and taught at the Hannover Medical School (MHH). Dirk Bumann has been an associate professor since 2007, and has been a full professor for infection biology at the Biozentrum of the University of Basel since 2015.

Act

Dirk Bumann focuses on research into the pathogenic metabolic processes of the pathogens Salmonella and Shigella , which lead to typhoid and diarrheal diseases. He investigates how these pathogens obtain nutrients from their host , coordinate the individual activities in metabolic networks and, through their growth, cause diseases . Dirk Bumann was also able to show that salmonella in the intestinal cells are initially marked by attaching ubiquitin and then linked to the phosphorylated protein optineurin. This way, special cell organelles , the autophagosomes, can recognize and eliminate bacteria . Bumann's research results are used to develop new therapeutic approaches for infectious diseases.

Awards

Publications (selection)

Complete list of publications

  • B. Steeb, B. Claudi, NA Burton, P. Tienz, A. Schmidt, H. Farhan, A. Mazé, D. Bumann: Parallel exploitation of diverse host nutrients enhances Salmonella virulence. In: PLOS Pathogens . 9 (4) Apr 2013, p. E1003301. PMID 23633950 .
  • P. Wild, H. Farhan, DG McEwan, S. Wagner, VV Rogov, NR Brady, B. Richter, J. Korac, O. Waidmann, C. Choudhary, V. Dötsch, D. Bumann, I. Dikic: Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth. In: Science . 333 (6039), Jul 8, 2011, pp. 228-233. PMID 21617041 .
  • D. Becker, M. Selbach, C. Rollenhagen, M. Ballmaier, TF Meyer, M. Mann, D. Bumann: Robust Salmonella metabolism limits possibilities for new antimicrobials. In: Nature . 440 (7082), Mar 16, 2006, pp. 303-307. PMID 16541065 .

Web links

Individual evidence

  1. a b Promotions and elections at the University of Basel
  2. Curriculum Vitae
  3. ^ Research group
  4. New antibiotics against resistant pathogens. ( Memento of November 2, 2013 in the Internet Archive ) at Biotechnologie.de, accessed on October 29, 2013.
  5. Europe's best young group leaders win EMBO support. at EurekAlert! (eurekalert.org) on ​​October 29, 2013.
  6. BD Research Award ( Memento of the original from November 3, 2013 in the Internet Archive ) Info: The archive link was automatically inserted and not yet checked. Please check the original and archive link according to the instructions and then remove this notice. at the German Society for Hygiene and Microbiology (DGHM), (dghm.org) on ​​October 29, 2013. @1@ 2Template: Webachiv / IABot / www.dghm.org
  7. Awarding of the Pettenkofer Prize 2015 ( memento from February 28, 2016 in the web archive archive.today ) at Ludwig Maximilians University, Munich, (mvp.uni-muenchen.de/) on February 24, 2016.
  8. Complete list of publications at Biozentrum.unibas.ch, accessed on June 23, 2014.