Flus pirils
Structural formula | |||||||||||||||||||
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Non-proprietary name | Flus pirils | ||||||||||||||||||
other names |
8- [4,4-bis (4-fluorophenyl) butyl] -1-phenyl-1,3,8-triazaspiro [4.5] decan-4-one ( IUPAC ) |
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Molecular formula | C 29 H 31 F 2 N 3 O | ||||||||||||||||||
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Drug information | |||||||||||||||||||
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properties | |||||||||||||||||||
Molar mass | 475.57 g · mol -1 | ||||||||||||||||||
Physical state |
firmly |
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Melting point |
188-190 ° C |
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
Fluspirilen is a drug that is used to treat schizophrenia . It is a highly effective neuroleptic from the group of diphenylbutylpiperidines .
The prescription medication is in Germany under the brand name Imap ® (an abbreviation for I ntra m uskuläres A NTI P sychotikum) and Fluspi ® and fluspirilene beta ® marketed. If the relevant indication is present (acute productive and chronic schizophrenic psychoses (long-term therapy and relapse prevention)), i. m. be injected.
In a study from 1997, fluspiril was shown to be the second most common cause of tardive dyskinesia after haloperidol . Just a few applications can be enough to trigger dyskinesias. This is another reason why it is warned against its use in the treatment of depression .
See also
Individual evidence
- ↑ a b c Data sheet Fluspirilene from Sigma-Aldrich , accessed on April 2, 2011 ( PDF ).
- ↑ Arzneitelegram 06/1997 .
- ↑ Arzneitelegram 06/1997 .