Friedrich Hartmut Dost

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Friedrich Hartmut Dost (born July 11, 1910 in Dresden , † November 2, 1985 in Gießen ) was a German pediatrician and the founder of pharmacokinetics .

Life

Hartmut Dost studied medicine in Rostock , Freiburg im Breisgau , Innsbruck and Leipzig , where he passed the state examination in 1933 and received his doctorate in 1934. In 1940 he completed his habilitation at the age of 30 and was a private lecturer in Leipzig in 1943. Dost was a member of the NSDAP , the SA and the National Socialist Medical Association .

After his captivity, he returned to the children's clinic in Leipzig in 1947. In 1951 he took over the provisional management of the children's clinic of the Charité at the Humboldt University in Berlin , where two years later he was appointed full professor of paediatrics and director of the children's clinic. In 1960 he followed the call of the Justus Liebig University in Giessen as director of the University Children's Clinic in Giessen .

Dost was a member of the German Academy of Sciences, the German Academy of Natural Scientists Leopoldina , Corresponding Member of the German Pharmacological Society, Corresponding Member of the Working Group for Pharmaceutical Process Engineering and Honorary Member of the German Society for Pediatrics. He was the recipient of the Curt Adam Prize of the Congress Society for Medical Further Education, the Otto Heubner Prize of the German Society for Pediatrics, the Schmiedeberg Plaque of the German Pharmacological Society, the Paul Martini Gold Medal and was awarded an honorary doctorate in the human medicine department of the Johann Wolfgang Goethe University Frankfurt am Main .

Reception / miscellaneous

Dost managed to find simple, validated rules for using successful drugs for newborns, infants and children. In fact, these drugs were originally intended for adults only. With the help of the pharmacokinetic calculation methods he developed, it was possible that children could also be treated. Parameters such as AUC ( Area Under the Curve ) are not missing from any pharmacokinetic publication. Pharmacokinetics has become an integral part of drug development. The European Medicines Agency ( EMA ) currently names 354 documents in which reference is made to this.

The Medical Society Gießen awards the Friedrich-Hartmut-Dost-Prize for special achievements in academic teaching in the department, the German Society for Clinical Pharmacology and Therapy e. V. the Friedrich-Hartmut-Dost-Gedächtnispreis for the promotion of clinical pharmacology in European countries. A street in his home town Dresden bears his name ( 51 ° 4 ′ 47.5 ″  N , 13 ° 45 ′ 6.1 ″  E ).

Web links

Individual evidence

  1. ↑ See Hartmut Dost's first and second matriculation in the Rostock matriculation portal
  2. ↑ a b Ernst Klee : The dictionary of persons on the Third Reich. Who was what before and after 1945 . Fischer Taschenbuch Verlag, Second updated edition, Frankfurt am Main 2005, p. 117.
personal data
SURNAME Dost, Friedrich Hartmut
BRIEF DESCRIPTION German pediatrician and founder of pharmacokinetics
DATE OF BIRTH July 11, 1910
PLACE OF BIRTH Dresden
DATE OF DEATH 2nd November 1985
Place of death to water